RANBP2 (RAN Binding Protein 2, RANBP2)
Short Description: RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008].
More information related to gene RANBP2.
More information related to gene RANBP2.
Products related to RANBP2 Gene:
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OriGene sr303980
RNAi
RANBP2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- RAN Binding Protein 2
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3343753
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to RANBP2
- RAN binding protein 2 (RANBP2)
- RAN binding protein 2 (Ranbp2)
- E3 SUMO-protein ligase RanBP2 (LOC474539)
- RAN binding protein 2 (ranbp2)
- E3 SUMO-protein ligase RanBP2 (LOC100511376)
- A430087B05Rik
- AI256741
- ANE1
- ane1
- IIAE3
- NUP358
- nup358
- RANBP2
- RGD1560047
- TRP1
- trp1
- TRP2
- trp2
Gene-IDs for different species
Protein level used designations for RANBP2
- 358 kDa nucleoporin
- E3 SUMO-protein ligase RanBP2
- P270
- nuclear pore complex protein Nup358
- nucleoporin 358
- nucleoporin Nup358
- ran-binding protein 2
- transformation-related protein 2
- RAN binding protein 2
- p270
- e3 SUMO-protein ligase RanBP2-like
Proteomics products related to RANBP2 Gene
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