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ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1, ROCK1)

Short Description: This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq, Jul 2008].
More information related to gene ROCK1.

Products related to ROCK1 Gene:

59 results

OriGene kn514977 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3225571
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn411547 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3225570
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc124118 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 2
Type:
cDNA
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_005406,NP_005397
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3391947
$1,720.62
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene rc211547 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_005406,NP_005397
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5382646
$1,834.47
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
OriGene rg211547 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_005406,NP_005397
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5382645
$2,032.47
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rc211547l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_005406,NP_005397
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5382649
$2,131.47
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene rc211547l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_005406,NP_005397
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5382648
$2,131.47
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene rc211547l2v ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN6411176
$2,378.97
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene rc211547l1v ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN6411175
$2,378.97
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 6 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ROCK1

  • Rho associated coiled-coil containing protein kinase 1 (ROCK1)
  • Rho kinase (Rok)
  • Rho-associated coiled-coil containing protein kinase 1 (Rock1)
  • Rho-associated, coiled-coil containing protein kinase 1 (rock1)
  • 1110055K06Rik
  • CG9774
  • Dmel\\CG9774
  • DRhk
  • DROK
  • DRok
  • Drok
  • dROK
  • dRok
  • drok
  • LOC100229794
  • P160Rock
  • P160ROCK
  • p160ROCK
  • Rhk
  • RhoK
  • ROCK
  • Rock
  • ROCK-1
  • Rock-I
  • ROCK-I
  • ROCK1
  • ROK
  • Rok
  • ROKalpha/beta

Gene-IDs for different species

Protein level used designations for ROCK1

  • Rho-associated coiled coil containing protein kinase 1
  • rho-associated protein kinase 1
  • Rho-associated, coiled-coil containing protein kinase 1
  • CG9774-PA
  • DRho-kinase
  • ROCK
  • Rho-associated kinase
  • RhoA kinase
  • drosophila rho-associated kinase
  • rho kinase
  • rok-PA
  • Rho-associated coiled-coil forming kinase 1
  • p160 ROCK-1
  • p160ROCK
  • rho-associated, coiled-coil-containing protein kinase 1
  • rho-associated, coiled-coil-containing protein kinase I
  • Rho-associated kinase beta
  • liver regeneration-related protein LRRG199
  • p150 RhoA-binding kinase ROK beta
  • Rho kinase
  • p160-ROCK
  • renal carcinoma antigen NY-REN-35
  • HEBM1
  • cAMP-dependent protein kinase ROCK-I
  • cePKA
  • corneal epithelial Rho-associated-Ser/Thr kinase 1
  • Rho-kinase beta
  • Rho-associated protein kinase 1
  • rho-associated coiled-coil domain-containing protein kinase 1
Other products related to ROCK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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