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ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1, ROCK1)

Short Description: This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq, Jul 2008].
More information related to gene ROCK1.

Products related to ROCK1 Gene:

59 results :

Human ROCK1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5734721
Datasheet
Catalog No. ABIN5734721
Type:
ORF
Application:
Cloning
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Synonyms:
ROCK1, Rok, Rock1, rock1
Insert length:
4065 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human ROCK1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4485894
Datasheet
Catalog No. ABIN4485894
Type:
cDNA
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Synonyms:
ROCK1, Rok, Rock1, rock1
Insert length:
4065 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat ROCK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_031098
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107829
Datasheet
Catalog No. ABIN5107829
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_031098
Species:
Rat
Synonyms:
ROCK1, Rok, Rock1, rock1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Rock1
Format:
Viral Particles
Storage:
-80 °C
Mouse ROCK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_009071
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107827
Datasheet
Catalog No. ABIN5107827
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_009071
Species:
Mouse
Synonyms:
ROCK1, Rok, Rock1, rock1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Rock1
Format:
Viral Particles
Storage:
-80 °C
Human ROCK1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_005406
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5107825
Datasheet
Catalog No. ABIN5107825
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_005406
Species:
Human
Synonyms:
ROCK1, Rok, Rock1, rock1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ROCK1
Format:
Viral Particles
Storage:
-80 °C
Human ROCK1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4839237
Datasheet
Catalog No. ABIN4839237
Type:
cDNA
Application:
Cloning
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Synonyms:
ROCK1, Rok, Rock1, rock1
Insert length:
4065 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ROCK1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4629365
Datasheet
Catalog No. ABIN4629365
Type:
cDNA
Application:
Cloning
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Synonyms:
ROCK1, Rok, Rock1, rock1
Insert length:
4065 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ROCK1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4710106
Datasheet
Catalog No. ABIN4710106
Type:
cDNA
Application:
Cloning
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Synonyms:
ROCK1, Rok, Rock1, rock1
Insert length:
4065 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human ROCK1 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4420808
Datasheet
Catalog No. ABIN4420808
Type:
cDNA
Application:
Protein Expression
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
Species:
Human
Synonyms:
ROCK1, Rok, Rock1, rock1
Insert length:
4065 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat ROCK1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_031098
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5223134
Datasheet
Catalog No. ABIN5223134
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1)
NCBI Accession:
NM_031098
Species:
Rat
Synonyms:
ROCK1, Rok, Rock1, rock1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Rock1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ROCK1

  • Rho associated coiled-coil containing protein kinase 1 (ROCK1)
  • Rho kinase (Rok)
  • Rho-associated coiled-coil containing protein kinase 1 (Rock1)
  • Rho-associated, coiled-coil containing protein kinase 1 (rock1)
  • 1110055K06Rik
  • CG9774
  • Dmel\\CG9774
  • DRhk
  • DROK
  • DRok
  • Drok
  • dROK
  • dRok
  • drok
  • LOC100229794
  • P160Rock
  • P160ROCK
  • p160ROCK
  • Rhk
  • RhoK
  • ROCK
  • Rock
  • ROCK-1
  • Rock-I
  • ROCK-I
  • ROCK1
  • ROK
  • Rok
  • ROKalpha/beta

Gene-IDs for different species

Protein level used designations for ROCK1

  • Rho-associated coiled coil containing protein kinase 1
  • rho-associated protein kinase 1
  • Rho-associated, coiled-coil containing protein kinase 1
  • CG9774-PA
  • DRho-kinase
  • ROCK
  • Rho-associated kinase
  • RhoA kinase
  • drosophila rho-associated kinase
  • rho kinase
  • rok-PA
  • Rho-associated coiled-coil forming kinase 1
  • p160 ROCK-1
  • p160ROCK
  • rho-associated, coiled-coil-containing protein kinase 1
  • rho-associated, coiled-coil-containing protein kinase I
  • Rho-associated kinase beta
  • liver regeneration-related protein LRRG199
  • p150 RhoA-binding kinase ROK beta
  • Rho kinase
  • p160-ROCK
  • renal carcinoma antigen NY-REN-35
  • HEBM1
  • cAMP-dependent protein kinase ROCK-I
  • cePKA
  • corneal epithelial Rho-associated-Ser/Thr kinase 1
  • Rho-kinase beta
  • Rho-associated protein kinase 1
  • rho-associated coiled-coil domain-containing protein kinase 1
Other products related to ROCK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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