Separase (Extra Spindle Poles Like 1, ESPL1)
Short Description: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21\; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010].
More information related to gene Separase.
More information related to gene Separase.
Products related to Separase Gene:
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42 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Extra Spindle Poles Like 1 (ESPL1)
- NCBI Accession:
- NM_012291
- Gene ID:
- 9700 (Human, ESPL1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4917209
$1,319.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 2 to 5 Business Days
OriGene sr306469
RNAi
ESPL1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Extra Spindle Poles Like 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3346229
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to Separase
- extra spindle pole bodies like 1, separase (ESPL1)
- extra spindle poles like 1 (espl1)
- extra spindle pole bodies 1, separase (Espl1)
- extra spindle pole bodies like 1, separase (Espl1)
- AL024103
- AU045071
- Cerp
- ESP1
- mp:zf637-3-001691
- PRCE
- SEPA
- SSE
Gene-IDs for different species
Protein level used designations for Separase
- caspase-like protein ESPL1
- extra spindle poles like 1
- extra spindle poles-like 1 protein
- separin
- separin, cysteine protease
- cds
- separase
- cease&desist
- zf637-3-001691
- Cut1/ESP1 related protein
Proteomics products related to Separase Gene
Other products related to Separase such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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