SH2D1A (SH2 Domain Containing 1A, SH2D1A)
Short Description: This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene SH2D1A.
More information related to gene SH2D1A.
Products related to SH2D1A Gene:
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OriGene rc225074
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SH2 Domain Containing 1A (SH2D1A)
- NCBI Accession:
- NM_001114937,NP_001108409
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5457767
$317.90
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SH2 Domain Containing 1A (SH2D1A)
- NCBI Accession:
- NM_001114937
- Gene ID:
- 4068 (Human, SH2D1A)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4923800
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SH2 Domain Containing 1A (SH2D1A)
- NCBI Accession:
- NM_002351
- Gene ID:
- 4068 (Human, SH2D1A)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4935464
OriGene sr402110
RNAi
SH2D1A
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- SH2 Domain Containing 1A
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3276138
$569.80
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to SH2D1A
- SH2 domain containing 1A (SH2D1A)
- SH2 domain containing 1A (Sh2d1a)
- DSHP
- EBVS
- Gm686
- IMD5
- LYP
- MTCP1
- RGD1562408
- SAP
- SAP/SH2D1A
- SH2D1A
- XLP
- XLPD
Gene-IDs for different species
Protein level used designations for SH2D1A
- Duncan disease SH2-protein
- SH2 domain-containing protein 1A
- SLAM associated protein/SH2 domain protein 1A
- SLAM-associated protein
- T cell signal transduction molecule SAP
- T-cell signal transduction molecule SAP
- signaling lymphocyte activation molecule-associated protein
- signaling lymphocytic activation molecule-associated protein
- SH2 domain protein 1A
- SH2 domain protein 1A, Duncan's disease (lymphoproliferative syndrome)
- Signaling lymphocytic activation molecule-associated protein
- Duncan disease homolog
Proteomics products related to SH2D1A Gene
Other products related to SH2D1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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