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SHC1 (SHC (Src Homology 2 Domain Containing) Transforming Protein 1, SHC1)

Short Description: This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
More information related to gene SHC1.

Products related to SHC1 Gene:

87 results

ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1)
NCBI Accession:
NM_183001
Gene ID:
6464 (Human, SHC1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4923763
$439.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1)
NCBI Accession:
NM_001130040
Gene ID:
6464 (Human, SHC1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4923764
$439.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1)
NCBI Accession:
NM_001130041
Gene ID:
6464 (Human, SHC1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4923765
$319.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene sc309335 cDNA PExp Mammalian Expression Vector pCMV6-XL6 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1)
NCBI Accession:
NM_183001,NP_892113
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, SP6 Promoter
Expression:
Transient
Catalog No. ABIN3393789
$538.56
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1)
NCBI Accession:
NM_003029
Gene ID:
6464 (Human, SHC1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4935447
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
OriGene sc126613 cDNA PExp Mammalian Expression Vector pCMV6-XL6 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
SHC (Src Homology 2 Domain Containing) Transforming Protein 1 (SHC1)
NCBI Accession:
NM_003029,NP_003020
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, SP6 Promoter
Expression:
Transient
Catalog No. ABIN3393788
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sr304361 RNAi SHC1 Species: Human HPLC purified
Application:
RNA Interference
Gene:
SHC (Src Homology 2 Domain Containing) Transforming Protein 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3344133
$435.60
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-XL6
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SHC1

  • SHC adaptor protein 1 (SHC1)
  • Shc1p (SHC1)
  • squalene--hopene cyclase (shc1)
  • SHC adaptor protein 1 (Shc1)
  • SHC (Src homology 2 domain containing) transforming protein 1 (shc1)
  • SHC (Src homology 2 domain containing) transforming protein 1 L homeolog (shc1.L)
  • src homology 2 domain-containing transforming protein C1 (Shc1)
  • p66
  • P66shc
  • p66shc
  • SHC
  • shc
  • Shc
  • SHC1
  • SHCA
  • ShcA
  • si:dkey-246i14.4
  • wu:fc10h03

Gene-IDs for different species

Protein level used designations for SHC1

  • SHC (Src homology 2 domain containing) transforming protein 1
  • Shc1p
  • Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH
  • squalene--hopene cyclase
  • SH2 domain protein C1
  • SHC-transforming protein 1
  • src homology 2 domain-containing-transforming protein C1
  • SHC-transforming protein 1-like
  • SHC (Src homology 2 domain-containing) transforming protein 1
  • SHC-transforming protein 3
  • SHC-transforming protein A
  • src homology 2 domain-containing transforming protein C1
  • p60Shc
  • src homology collagen
  • adaptor protein SHC
Other products related to SHC1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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