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SHP1 (Protein-tyrosine Phosphatase 1C, PTPN6)

Short Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].
More information related to gene SHP1.

Products related to SHP1 Gene:

76 results

OriGene tl712250 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Protein-tyrosine Phosphatase 1C (PTPN6)
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3449526
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tr515795 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Protein-tyrosine Phosphatase 1C (PTPN6)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3548794
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene kn514220 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Protein-tyrosine Phosphatase 1C (PTPN6)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3232572
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn400728 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Protein-tyrosine Phosphatase 1C (PTPN6)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3232571
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sr417951 RNAi PTPN6 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Protein-tyrosine Phosphatase 1C
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3265482
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr508704 RNAi PTPN6 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Protein-tyrosine Phosphatase 1C
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3358012
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sc320627 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein-tyrosine Phosphatase 1C (PTPN6)
NCBI Accession:
NM_080548,NP_536858
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3318123
$551.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc109665 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein-tyrosine Phosphatase 1C (PTPN6)
NCBI Accession:
NM_002831,NP_002822
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3379618
$549.45
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene mc219479 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein-tyrosine Phosphatase 1C (PTPN6)
NCBI Accession:
NM_013545,NP_038573
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3366387
$603.90
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc219501 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein-tyrosine Phosphatase 1C (PTPN6)
NCBI Accession:
NM_001077705,NP_001071173
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3366388
$551.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-AC
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SHP1

  • protein tyrosine phosphatase, non-receptor type 6 (PTPN6)
  • protein tyrosine phosphatase, non-receptor type 6 (Ptpn6)
  • protein tyrosine phosphatase, non-receptor type 6 (ptpn6)
  • protein tyrosine phosphatase, non-receptor type 6 L homeolog (ptpn6.L)
  • DRPLA
  • fj22f05
  • HCPH
  • Hcph
  • HPTP1C
  • me
  • motheaten
  • PTP-1C
  • Ptp1C
  • Ptph6
  • ptpn6
  • SH-PTP1
  • SHP-1
  • Shp-1
  • SHP-1L
  • SHP1
  • wu:fj22f05
  • zgc:55501

Gene-IDs for different species

Protein level used designations for SHP1

  • hematopoietic cell phosphatase
  • hematopoietic cell protein-tyrosine phosphatase
  • protein-tyrosine phosphatase 1C
  • protein-tyrosine phosphatase SHP-1
  • tyrosine-protein phosphatase non-receptor type 6
  • dentatorubro-pallidoluysian atrophy protein
  • non-receptor type protein tyrosine phosphatase SHP1
  • 70Z-SHP
  • PTP-1C
  • PTPTY-42
  • SH-PTP1
  • hemopoietic cell phosphatase
  • SH2 phosphatase 1
  • protein tyrosine phosphatase, non-receptor type 6 L homeolog
Other products related to SHP1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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