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SIGIRR (Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain, SIGIRR)

Short Description: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP (By similarity).
More information related to gene SIGIRR.

Products related to SIGIRR Gene:

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58 results

Human SIGIRR ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg201356 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5457911
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human SIGIRR ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg225643 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5457913
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human SIGIRR ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc225642 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
NCBI Accession:
NM_001135053,NP_001128525
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5457915
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human SIGIRR ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc201356 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
NCBI Accession:
NM_021805,NP_068577
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5457914
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human SIGIRR ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc225643 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
NCBI Accession:
NM_001135054,NP_001128526
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5457916
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Rat SIGIRR ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rr203114 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
NCBI Accession:
NM_001024887,NP_001020058
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5457917
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human SIGIRR ORF Clone in Lentiviral Vector (Myc-DYKDDDDK Tag)
OriGene rc201356l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
NCBI Accession:
NM_021805,NP_068577
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5457922
$749.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human SIGIRR ORF Clone in Lentiviral Vector (GFP tag)
OriGene rc201356l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Single Immunoglobulin and Toll-Interleukin 1 Receptor (TIR) Domain (SIGIRR)
NCBI Accession:
NM_021805,NP_068577
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5457918
$749.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SIGIRR

  • single Ig and TIR domain containing (SIGIRR)
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (Sigirr)
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain (sigirr)
  • single Ig and TIR domain containing (Sigirr)
  • AI256711
  • RGD1306732
  • sc:d148
  • TIR8

Gene-IDs for different species

Protein level used designations for SIGIRR

  • single Ig IL-1-related receptor
  • single Ig IL-1R-related molecule
  • single immunoglobulin domain IL1R1 related
  • single immunoglobulin domain-containing IL1R-related protein
  • toll/interleukin-1 receptor 8
  • single Ig IL-1 receptor related protein
  • single Ig IL-1R-related protein
  • TIR8
Other products related to SIGIRR such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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