SLC12A1 (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1, SLC12A1)
Short Description: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010].
More information related to gene SLC12A1.
More information related to gene SLC12A1.
Products related to SLC12A1 Gene:
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OriGene sr304438
RNAi
SLC12A1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3344210
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
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Synonyms and alternative names related to SLC12A1
- si:ch211-220f12.1 (si:ch211-220f12.1)
- solute carrier family 12 member 1 (SLC12A1)
- solute carrier family 12 member 1 (Slc12a1)
- solute carrier family 12, member 1 (Slc12a1)
- AI788571
- BSC1
- D630042G03Rik
- DKFZp469A2020
- mBSC1
- NKCC2
- Nkcc2
- slc12a1
- SLC12A1
- urehr3
Gene-IDs for different species
Protein level used designations for SLC12A1
- FERM domain-containing protein 4A
- Na/K/Cl cotransporter
- solute carrier family 12 (sodium/potassium/chloride transporters), member 1
- solute carrier family 12 member 1-like
- NKCC2A variant A
- Na-K-2Cl cotransporter
- bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
- kidney-specific Na-K-Cl symporter
- solute carrier family 12 member 1
- Solute carrier family 12 member 1 (bumetanide-sensitive sodium-[potassium]-chloride cotransporter)
- Solute carrier family 12, member 1 (bumetanide-sensitive sodium-[potassium]-chloride cotransporter)
- apical Na(2Cl)K cotransporter
- solute carrier family 12, member 1
- BSC1
- bumetanide-sensitive cotransporter type 1
Proteomics products related to SLC12A1 Gene
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