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SLC12A3 (Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3, SLC12A3)

Short Description: This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene SLC12A3.

Products related to SLC12A3 Gene:

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69 results

Human SLC12A3 ORF Clone in Lentiviral Vector (Myc-DYKDDDDK Tag)
OriGene rc221919l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_000339,NP_000330
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5382898
$1,185.03
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human SLC12A3 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc221919 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_000339,NP_000330
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5382890
$888.03
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human SLC12A3 ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg226300 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5382888
$1,166.22
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
Details
Details
Human SLC12A3 ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg226304 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5382889
$1,173.15
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
Details
Details
Human SLC12A3 ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg221919 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5382887
$1,086.03
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human SLC12A3 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_001126108
Gene ID:
6559 (Human, SLC12A3)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4945274
$1,029.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Details
Details
Human SLC12A3 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_001126107
Gene ID:
6559 (Human, SLC12A3)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4945275
$1,039.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Details
Details
Human SLC12A3 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3 (SLC12A3)
NCBI Accession:
NM_000339
Gene ID:
6559 (Human, SLC12A3)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4945276
$1,039.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 2 to 5 Business Days
Details
Details
Human SLC12A3 siRNA Oligo
OriGene sr304440 RNAi SLC12A3 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Solute Carrier Family 12 (Sodium/Chloride Transporters), Member 3
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3344212
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SLC12A3

  • solute carrier family 12 member 3 (SLC12A3)
  • solute carrier family 12 (sodium/chloride transporter), member 3 (slc12a3.2)
  • solute carrier family 12 member 3 (Slc12a3)
  • solute carrier family 12, member 3 (Slc12a3)
  • AI035291
  • DKFZp469N2315
  • NCC
  • NCCT
  • SLC12A3
  • slc12a3
  • TSC

Gene-IDs for different species

Protein level used designations for SLC12A3

  • solute carrier family 12 (sodium/chloride transporters), member 3
  • thiazide-sensitive sodium chloride cotransporter
  • solute carrier family 12 (sodium/chloride transporters), member 3, gene 2
  • solute carrier family 12 member 3-like
  • Na-Cl cotransporter
  • Na-Cl symporter
  • NaCl electroneutral thiazide-sensitive cotransporter
  • solute carrier family 12 member 3
  • thiazide-sensitive Na-Cl cotransporter
  • thiazide-sensitive sodium-chloride cotransporter
  • solute carrier family 12, member 3
  • sodium chloride cotransporter
Other products related to SLC12A3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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