SMCR8 (Smith-Magenis Syndrome Chromosome Region, Candidate 8, SMCR8)
Short Description: Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. {ECO:0000250|UniProtKB:Q8TEV9}.
More information related to gene SMCR8.
More information related to gene SMCR8.
Products related to SMCR8 Gene:
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57 results
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
- NCBI Accession:
- NM_144775
- Gene ID:
- 140775 (Human, SMCR8)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4918060
$679.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene rc212285l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
- NCBI Accession:
- NM_144775,NP_658988
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5494357
$1,571.13
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc212285l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
- NCBI Accession:
- NM_144775,NP_658988
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5494356
$1,571.13
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rr217347
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5494355
$932.58
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc212285
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
- NCBI Accession:
- NM_144775,NP_658988
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5494354
$1,274.13
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg212285
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Smith-Magenis Syndrome Chromosome Region, Candidate 8 (SMCR8)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5494353
$1,472.13
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 31 to 32 Business Days
OriGene sr315391
RNAi
SMCR8
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Smith-Magenis Syndrome Chromosome Region, Candidate 8
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3312392
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to SMCR8
- Smith-Magenis syndrome chromosome region, candidate 8 (SMCR8)
- Smith-Magenis syndrome chromosome region, candidate 8 homolog (human) (Smcr8)
- Smith-Magenis syndrome chromosome region, candidate 8 (Smcr8)
- Smith-Magenis syndrome chromosome region, candidate 8b (smcr8b)
- 2310076G09Rik
- AI642055
- D030073L15Rik
- RGD1564621
- smcr8
Gene-IDs for different species
Protein level used designations for SMCR8
- Smith-Magenis syndrome chromosomal region candidate gene 8 protein
- Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog
- Smith-Magenis syndrome chromosome region, candidate 8 homolog
- Smith-Magenis syndrome chromosomal region candidate gene 8 protein homolog B
- guanine nucleotide exchange protein smcr8b
- smith-Magenis syndrome chromosomal region candidate gene 8-B protein homolog
Proteomics products related to SMCR8 Gene
Other products related to SMCR8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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