SPAG1 (Sperm Associated Antigen 1, SPAG1)
Short Description: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein. [provided by RefSeq, Jul 2008].
More information related to gene SPAG1.
More information related to gene SPAG1.
Products related to SPAG1 Gene:
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OriGene sr304542
RNAi
SPAG1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Sperm Associated Antigen 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3344314
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to SPAG1
- sperm associated antigen 1 (SPAG1)
- sperm associated antigen 1a (spag1a)
- sperm associated antigen 1 (CpipJ_CPIJ006297)
- sperm associated antigen 1 (spag1)
- sperm associated antigen 1 (Spag1)
- cb1089
- hsd-3.8
- HSD-3.8
- MGC162178
- sp75
- SP75
- tpis
- TPIS
- wu:fj78g10
Gene-IDs for different species
Protein level used designations for SPAG1
- sperm associated antigen 1
- sperm-associated antigen 1
- TPR-containing protein involved in spermatogenesis
- infertility-related sperm protein Spag-1
- tetratricopeptide repeat-containing protein
- HSD-3.8
Proteomics products related to SPAG1 Gene
Other products related to SPAG1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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