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SPEN (Spen Homolog, Transcriptional Regulator, SPEN)

Short Description: This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator\; this binding can modulate the activity of both liganded and nonliganded steroid receptors. [provided by RefSeq, Jul 2008].
More information related to gene SPEN.

Products related to SPEN Gene:

25 results

OriGene kn413922 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Spen Homolog, Transcriptional Regulator (Drosophila) (SPEN)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3255441
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sr423656 RNAi SPEN Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Spen Homolog, Transcriptional Regulator
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3350494
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene rc213922 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Spen Homolog, Transcriptional Regulator (Drosophila) (SPEN)
NCBI Accession:
NM_015001,NP_055816
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5457855
$4,326.30
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 41 to 42 Business Days
OriGene rg213922 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Spen Homolog, Transcriptional Regulator (SPEN)
NCBI Accession:
NM_015001,NP_055816
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5457854
$4,524.30
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 41 to 42 Business Days
OriGene sr307935 RNAi SPEN Species: Human HPLC purified
Application:
RNA Interference
Gene:
Spen Homolog, Transcriptional Regulator
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3283974
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Mouse
    • Human
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCMV6-Entry
    • pCas-Guide
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Retroviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
  • Insert
    • shRNA
    • cDNA
    • gRNA + Cas9
    • gRNA
    • ORF
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to SPEN

  • spen family transcriptional repressor (SPEN)
  • SPEN homolog, transcriptional regulator (Drosophila) (Spen)
  • HIAA0929
  • MINT
  • Mint
  • mKIAA0929
  • RBM15C
  • SHARP

Gene-IDs for different species

Protein level used designations for SPEN

  • Msx2 interacting nuclear target (MINT) homolog
  • SMART/HDAC1 associated repressor protein
  • SMART/HDAC1-associated repressor protein
  • msx2-interacting protein
  • nuclear receptor transcription cofactor
  • spen homolog, transcriptional regulator (Drosophila)
  • Msx2 interacting nuclear target protein
Other products related to SPEN such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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