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SPTLC3 (Serine Palmitoyltransferase, Long Chain Base Subunit 3, SPTLC3)

Short Description: The SPTLC3 gene encodes an isoform of the third subunit of serine palmitoyltransferase (SPT\; EC 2.3.1.50), which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al., 2006 [PubMed 17023427]). SPT contains 2 main subunits: the common SPTLC1 subunit (MIM 605712) and either SPTLC2 (MIM 605713) or its isoform SPTLC2L (SPTLC3), depending on the tissue in which biosynthesis occurs (Hornemann et al., 2006 [PubMed 17023427]). There are also 2 highly related isoforms of a third subunit, SSSPTA (MIM 613540) and SSSPTB (MIM 610412), that confer acyl-CoA preference of the SPT enzyme and are essential for maximal enzyme activity (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010].
More information related to gene SPTLC3.

Products related to SPTLC3 Gene:

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59 results

Rat SPTLC3 siRNA Oligo
OriGene sr501818 RNAi SPTLC3 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3352098
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Rat SPTLC3 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rn202104 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_001106517,NP_001099987
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3372057
$571.23
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Mouse SPTLC3 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc219046 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_175467,NP_780676
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3372056
$571.23
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human SPTLC3 cDNA Clone in Mammalian Expression Vector
OriGene sc113546 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_018327,NP_060797
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3386952
$1,106.82
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human SPTLC3 ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg224216 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5389136
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human SPTLC3 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc224216 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_018327,NP_060797
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5389137
$286.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Rat SPTLC3 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rr202104 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_001106517,NP_001099987
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5389138
$570.24
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human SPTLC3 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3 (SPTLC3)
NCBI Accession:
NM_018327
Gene ID:
55304 (Human, SPTLC3)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4923092
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human SPTLC3 siRNA Oligo
OriGene sr310663 RNAi SPTLC3 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Serine Palmitoyltransferase, Long Chain Base Subunit 3
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3286698
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SPTLC3

  • serine palmitoyltransferase long chain base subunit 3 (SPTLC3)
  • serine palmitoyltransferase, long chain base subunit 3 S homeolog (sptlc3.S)
  • serine palmitoyltransferase 3 (LOC100438231)
  • serine palmitoyltransferase, long chain base subunit 3 (sptlc3)
  • serine palmitoyltransferase 3 (LOC100546896)
  • serine palmitoyltransferase long chain base subunit 3 (sptlc3)
  • serine palmitoyltransferase, long chain base subunit 3 (Sptlc3)
  • C20orf38
  • C130053K05Rik
  • dJ718P11
  • dJ718P11.1
  • hLCB2b
  • LCB2B
  • LCB3
  • MGC130979
  • RGD1310030
  • SPT3
  • SPTLC2L

Gene-IDs for different species

Protein level used designations for SPTLC3

  • serine palmitoyltransferase, long chain base subunit 3
  • serine palmitoyltransferase, long chain base subunit 2-like (aminotransferase 2)
  • serine palmitoyltransferase 3-like
  • serine palmitoyltransferase 3
  • LCB 3
  • SPT 3
  • long chain base biosynthesis protein 2b
  • long chain base biosynthesis protein 3
  • serine-palmitoyl-CoA transferase 3
  • LCB2b
Other products related to SPTLC3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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