TAB1 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1, TAB1)
Short Description: The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
More information related to gene TAB1.
More information related to gene TAB1.
Products related to TAB1 Gene:
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62 results
OriGene rc208522l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1)
- NCBI Accession:
- NM_006116,NP_006107
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5439788
$993.96
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr307092
RNAi
TAB1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3346847
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to TAB1
- TGF-beta activated kinase 1 (MAP3K7) binding protein 1 (TAB1)
- TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1)
- 3'-Tab1
- 2310012M03Rik
- b2b449Clo
- MAP3K7IP1
- Map3k7ip1
Gene-IDs for different species
Protein level used designations for TAB1
- TAK1-binding protein 1
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
- mitogen-activated protein kinase kinase kinase 7-interacting protein 1
- transforming growth factor beta-activated kinase-binding protein 1
- TGF-beta-activated kinase 1-binding protein 1
- Tak1-binding protein 1
- beta activated kinase-1 binding protein-1
- mitogen activated protein kinase kinase kinase 7 interacting protein 1
- mitogen-activated protein kinase kinase kinase 7 interacting protein 1
Proteomics products related to TAB1 Gene
Other products related to TAB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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