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TDP1 (Tyrosyl-DNA Phosphodiesterase 1, TDP1)

Short Description: The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008].
More information related to gene TDP1.

Products related to TDP1 Gene:

62 results

OriGene sr310932 RNAi TDP1 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Tyrosyl-DNA Phosphodiesterase 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3286964
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
Tyrosyl-DNA Phosphodiesterase 1 (TDP1)
Gene ID:
55775 (Human, TDP1)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5316176
$215.19
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 19 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC
    • pCMV6-XL4
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to TDP1

  • tyrosyl-DNA phosphodiesterase 1 (TDP1)
  • tyrosyl-DNA Phosphodiesterase (Tdp1) (Tc00.1047053511191.10)
  • tyrosyl-DNA phosphodiesterase 1 (Tdp1)
  • tyrosyl-DNA phosphodiesterase 1 L homeolog (tdp1.L)
  • tyrosyl-DNA phosphodiesterase 1 (tdp1)
  • tyrosyl-DNA phosphodiesterase-like protein (TDP1)
  • tyrosyl-DNA phosphodiesterase 1 (PTRG_11198)
  • tyrosyl-DNA phosphodiesterase 1 (MCYG_02121)
  • tyrosyl-DNA phosphodiesterase 1 (MGYG_03035)
  • 2810481F14Rik
  • 4921509N21Rik
  • AI838772
  • AW493413
  • E430034L06Rik
  • F8M21.60
  • F8M21_60
  • MGC83708
  • MLZ-501
  • SCAN1
  • tdp1
  • TDP1
  • tyrosyl-DNA phosphodiesterase 1

Gene-IDs for different species

Protein level used designations for TDP1

  • tyr-DNA phosphodiesterase 1
  • tyrosyl-DNA Phosphodiesterase (Tdp1)
  • protein expressed in male leptotene and zygotene spermatocytes 501
  • tyrosyl-DNA phodphodiesterase 1
  • tyrosyl-DNA phosphodiesterase 1
  • tyrosyl-DNA phosphodiesterase 1-like
  • Tyrosyl-DNA phosphodiesterase 1-like protein
Other products related to TDP1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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