TDP1 (Tyrosyl-DNA Phosphodiesterase 1, TDP1)
Short Description: The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008].
More information related to gene TDP1.
More information related to gene TDP1.
Products related to TDP1 Gene:
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OriGene rc214927l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tyrosyl-DNA Phosphodiesterase 1 (TDP1)
- NCBI Accession:
- NM_018319,NP_060789
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5367217
$857.34
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr310932
RNAi
TDP1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Tyrosyl-DNA Phosphodiesterase 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3286964
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to TDP1
- tyrosyl-DNA phosphodiesterase 1 (TDP1)
- tyrosyl-DNA Phosphodiesterase (Tdp1) (Tc00.1047053511191.10)
- tyrosyl-DNA phosphodiesterase 1 (Tdp1)
- tyrosyl-DNA phosphodiesterase 1 L homeolog (tdp1.L)
- tyrosyl-DNA phosphodiesterase 1 (tdp1)
- tyrosyl-DNA phosphodiesterase-like protein (TDP1)
- tyrosyl-DNA phosphodiesterase 1 (PTRG_11198)
- tyrosyl-DNA phosphodiesterase 1 (MCYG_02121)
- tyrosyl-DNA phosphodiesterase 1 (MGYG_03035)
- 2810481F14Rik
- 4921509N21Rik
- AI838772
- AW493413
- E430034L06Rik
- F8M21.60
- F8M21_60
- MGC83708
- MLZ-501
- SCAN1
- tdp1
- TDP1
- tyrosyl-DNA phosphodiesterase 1
Gene-IDs for different species
Protein level used designations for TDP1
- tyr-DNA phosphodiesterase 1
- tyrosyl-DNA Phosphodiesterase (Tdp1)
- protein expressed in male leptotene and zygotene spermatocytes 501
- tyrosyl-DNA phodphodiesterase 1
- tyrosyl-DNA phosphodiesterase 1
- tyrosyl-DNA phosphodiesterase 1-like
- Tyrosyl-DNA phosphodiesterase 1-like protein
Proteomics products related to TDP1 Gene
Other products related to TDP1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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