TET1 (Tet Methylcytosine Dioxygenase 1, TET1)
Short Description: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC). Might initiate a process leading to cytosine demethylation through deamination into 5- hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. Preferentially binds to CpG-rich sequences at promoters of both transcriptionally active and polycomb-repressed genes. By controlling the levels of 5mC and 5hmC at gene promoters, it may regulate the gene expression silencing induced by cytosine methylation. May have a dual function by also repressing the expression of a subset of genes through recruitment of transcriptional repressors to promoters. Involved in the balance between pluripotency and lineage commitment of cells it plays a role in embryonic stem cells maintenance and inner cell mass cell specification.
More information related to gene TET1.
More information related to gene TET1.
Products related to TET1 Gene:
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50 results
OriGene kn418608
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3257067
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc225115
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- NCBI Accession:
- NM_027384,NP_081660
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3336027
$2,624.49
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 61 to 62 Business Days
OriGene rn203297
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- NCBI Accession:
- NM_001107643,NP_001101113
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3336029
$617.76
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene mc229698
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- NCBI Accession:
- NM_001253857,NP_001240786
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3336028
$1,833.48
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
OriGene sc305272
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- NCBI Accession:
- NM_030625,NP_085128
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3392645
$1,746.36
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- NCBI Accession:
- NM_030625
- Gene ID:
- 80312 (Human, TET1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4946371
$1,319.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 2 to 5 Business Days
OriGene rc218608
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- NCBI Accession:
- NM_030625,NP_085128
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5473394
$1,745.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc218608l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- NCBI Accession:
- NM_030625,NP_085128
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5473395
$2,042.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg218608
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Tet Methylcytosine Dioxygenase 1 (TET1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5473393
$2,141.37
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr312887
RNAi
TET1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Tet Methylcytosine Dioxygenase 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3288917
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to TET1
- tet methylcytosine dioxygenase 1 (TET1)
- tet methylcytosine dioxygenase 1 (Tet1)
- solute carrier family 25 member 16 (SLC25A16)
- 2510010B09Rik
- AA517754
- bA119F7.1
- BB001228
- CXXC6
- Cxxc6
- D10Ertd17e
- LCX
- mKIAA1676
Gene-IDs for different species
Protein level used designations for TET1
- CXXC finger 6
- CXXC zinc finger 6
- CXXC-type zinc finger protein 6
- leukemia-associated protein with a CXXC domain
- methylcytosine dioxygenase TET1
- ten-eleven translocation 1 gene protein
- ten-eleven translocation-1
- tet oncogene 1
- ten-eleven translocation 1 gene protein homolog
- tet methylcytosine dioxygenase 1
Proteomics products related to TET1 Gene
Other products related to TET1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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