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TGS1 (Trimethylguanosine Synthase 1, TGS1)

Short Description: Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation (By similarity).
More information related to gene TGS1.

Products related to TGS1 Gene:

53 results

OriGene rg221904 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Trimethylguanosine Synthase 1 (TGS1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5452673
$971.19
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene rr205951 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Trimethylguanosine Synthase 1 (TGS1)
NCBI Accession:
NM_001107904,NP_001101374
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5490163
$847.44
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene sr314326 RNAi TGS1 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Trimethylguanosine Synthase 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3311328
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • His-GST
    • His-MBP
    • Myc-DYKDDDDK Tag
    • HA tag
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pPB-His-GST
    • pPB-His-MBP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL6
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
    • ORF
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • T7 Promoter
    • CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to TGS1

  • trimethylguanosine synthase 1 (TGS1)
  • trimethylguanosine synthase 1 (Tgs1)
  • trimethylguanosine synthase 1 L homeolog (tgs1.L)
  • D4Ertd800e
  • NCOA6IP
  • Ncoa6ip
  • PIMT
  • Pimt
  • PIPMT

Gene-IDs for different species

Protein level used designations for TGS1

  • CLL-associated antigen KW-2
  • PRIP-interacting protein PIPMT
  • PRIP-interacting protein with methyltransferase domain
  • PRIP-interacting protein with methyltransferase motif
  • SEREX-defined
  • cap-specific guanine-N2 methyltransferase
  • hepatocellular carcinoma-associated antigen 137
  • nuclear receptor coactivator 6 interacting protein
  • nuclear receptor coactivator 6-interacting protein
  • trimethylguanosine synthase
  • trimethylguanosine synthase homolog
  • PIPMT
  • PIMT
  • LOW QUALITY PROTEIN: trimethylguanosine synthase
Other products related to TGS1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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