THO Complex 5 (THO Complex 5, THOC5)
Short Description: Component the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. Regulates the expression of myeloid transcription factors CEBPA, CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate. May be involved in the differentiation of granulocytes and adipocytes. Essential for hematopoietic primitive cell survival and plays an integral role in monocytic development (By similarity).
More information related to gene THO Complex 5.
More information related to gene THO Complex 5.
Products related to THO Complex 5 Gene:
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OriGene sr305628
RNAi
THOC5
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- THO Complex 5
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3345393
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
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Synonyms and alternative names related to THO Complex 5
- THO complex 5 (THOC5)
- THO complex 5 (Thoc5)
- THO complex 5 (thoc5)
- THO complex 5 S homeolog (thoc5.S)
- THO complex 5 L homeolog (thoc5.L)
- 1700060C24Rik
- A430085L24Rik
- C22orf19
- fc54b09
- Fmip
- fmip
- fSAP79
- PK1.3
- Sgk2
- THOC5
- thoc5
- thoc5-a
- thoc5-b
- wu:fc54b09
- zgc:56190
- zgc:76912
Gene-IDs for different species
Protein level used designations for THO Complex 5
- Fms-interacting protein
- NF2/meningioma region protein pK1.3
- PP39.2
- THO complex subunit 5 homolog
- functional spliceosome-associated protein 79
- hTREX90
- placental protein 39.2
- Fms interacting protein
- fms-interacting protein
- serum/glucocorticoid regulated kinase 2
- protein C22orf19
- THO complex 5
- THO complex subunit 5 homolog-like
- THO complex subunit 5 homolog B
- THO complex subunit 5 homolog A
Proteomics products related to THO Complex 5 Gene
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