USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated), USP7)
Short Description: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6 (By similarity).
More information related to gene USP7.
More information related to gene USP7.
Products related to USP7 Gene:
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63 results
OriGene sc337847
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- NCBI Accession:
- NM_001286457,NP_001273386
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3339002
$1,030.59
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rr213504
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- NCBI Accession:
- NM_001024790,NP_001019961
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5450284
$1,045.44
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rn213504
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- NCBI Accession:
- NM_001024790,NP_001019961
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3339000
$1,046.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rc213986
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- NCBI Accession:
- NM_003470,NP_003461
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5450281
$1,424.61
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sc117955
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- NCBI Accession:
- NM_003470,NP_003461
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3387653
$1,425.60
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene mc223575
cDNA
PExp
Mammalian Expression Vector
pCMV6-AC-Myc-DDK
Ampicillin
Enhanced CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- NCBI Accession:
- NM_001003918,NP_001003918
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-Myc-DDK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN3320509
$1,426.59
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rg213986
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5450280
$1,622.61
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene kn318814
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3259902
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn213986
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3259901
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 10 to 13 Business Days
OriGene rc213986l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
- NCBI Accession:
- NM_003470,NP_003461
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5450287
$1,721.61
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
Synonyms and alternative names related to USP7
- Ubiquitin-specific protease 7 (Usp7)
- ubiquitin carboxyl-terminal hydrolase 7 (LOC100201254)
- ubiquitin specific peptidase 7 (USP7)
- ubiquitin specific peptidase 7 (Usp7)
- 2210010O09Rik
- AA409944
- AA617399
- AU019296
- AW548146
- C80752
- CG1490
- Dmel\\CG1490
- Hausp
- HAUSP
- TEF1
- UBP
- USP7
Gene-IDs for different species
Protein level used designations for USP7
- CG1490-PB
- Usp7-PB
- ubiquitin specific peptidase 7 (herpes virus-associated)
- ubiquitin carboxyl-terminal hydrolase 7-like
- deubiquitinating enzyme 7
- herpesvirus-associated ubiquitin-specific protease
- mHAUSP
- ubiquitin carboxyl-terminal hydrolase 7
- ubiquitin specific protease 7
- ubiquitin thioesterase 7
- ubiquitin thiolesterase 7
- ubiquitin-specific-processing protease 7
- Herpes virus-associated ubiquitin-specific protease
- ubiquitin specific protease 7 (herpes virus-associated)
- herpes-virus-associated ubiquitin-specific protease
- rHAUSP
- ubiquitin-specific peptidase 7
Proteomics products related to USP7 Gene
Other products related to USP7 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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