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USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated), USP7)

Short Description: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6 (By similarity).
More information related to gene USP7.

Products related to USP7 Gene:

63 results :

Rat USP7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001024790
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263475
Datasheet
Catalog No. ABIN5263475
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001024790
Species:
Rat
Synonyms:
Usp7, LOC100201254, USP7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Usp7
Format:
Viral Particles
Storage:
-80 °C
Mouse USP7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001003918
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263473
Datasheet
Catalog No. ABIN5263473
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001003918
Species:
Mouse
Synonyms:
Usp7, LOC100201254, USP7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Usp7
Format:
Viral Particles
Storage:
-80 °C
Human USP7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_003470
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263471
Datasheet
Catalog No. ABIN5263471
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_003470
Species:
Human
Synonyms:
Usp7, LOC100201254, USP7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of USP7
Format:
Viral Particles
Storage:
-80 °C
Rat USP7 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001024790
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147942
Datasheet
Catalog No. ABIN5147942
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001024790
Species:
Rat
Synonyms:
Usp7, LOC100201254, USP7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Usp7
Format:
Viral Particles
Storage:
-80 °C
Mouse USP7 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001003918
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147940
Datasheet
Catalog No. ABIN5147940
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001003918
Species:
Mouse
Synonyms:
Usp7, LOC100201254, USP7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Usp7
Format:
Viral Particles
Storage:
-80 °C
Human USP7 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_003470
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5147938
Datasheet
Catalog No. ABIN5147938
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_003470
Species:
Human
Synonyms:
Usp7, LOC100201254, USP7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of USP7
Format:
Viral Particles
Storage:
-80 °C
Mouse USP7 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001003918
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755408
Datasheet
Catalog No. ABIN5755408
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001003918
Species:
Mouse
Synonyms:
Usp7, LOC100201254, USP7
Insert length:
3312 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat USP7 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001024790
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755409
Datasheet
Catalog No. ABIN5755409
Type:
ORF
Application:
Cloning
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001024790
Species:
Rat
Synonyms:
Usp7, LOC100201254, USP7
Insert length:
3312 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat USP7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001024790
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263474
Datasheet
Catalog No. ABIN5263474
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001024790
Species:
Rat
Synonyms:
Usp7, LOC100201254, USP7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Usp7
Format:
Viral Particles
Storage:
-80 °C
Mouse USP7 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001003918
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263472
Datasheet
Catalog No. ABIN5263472
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7)
NCBI Accession:
NM_001003918
Species:
Mouse
Synonyms:
Usp7, LOC100201254, USP7
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Usp7
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pCMV6-AC-GFP
    • pCMV6-AC-Myc-DDK
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to USP7

  • Ubiquitin-specific protease 7 (Usp7)
  • ubiquitin carboxyl-terminal hydrolase 7 (LOC100201254)
  • ubiquitin specific peptidase 7 (USP7)
  • ubiquitin specific peptidase 7 (Usp7)
  • 2210010O09Rik
  • AA409944
  • AA617399
  • AU019296
  • AW548146
  • C80752
  • CG1490
  • Dmel\\CG1490
  • Hausp
  • HAUSP
  • TEF1
  • UBP
  • USP7

Gene-IDs for different species

Protein level used designations for USP7

  • CG1490-PB
  • Usp7-PB
  • ubiquitin specific peptidase 7 (herpes virus-associated)
  • ubiquitin carboxyl-terminal hydrolase 7-like
  • deubiquitinating enzyme 7
  • herpesvirus-associated ubiquitin-specific protease
  • mHAUSP
  • ubiquitin carboxyl-terminal hydrolase 7
  • ubiquitin specific protease 7
  • ubiquitin thioesterase 7
  • ubiquitin thiolesterase 7
  • ubiquitin-specific-processing protease 7
  • Herpes virus-associated ubiquitin-specific protease
  • ubiquitin specific protease 7 (herpes virus-associated)
  • herpes-virus-associated ubiquitin-specific protease
  • rHAUSP
  • ubiquitin-specific peptidase 7
Other products related to USP7 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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