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ABAT (4-Aminobutyrate Aminotransferase, ABAT)

Short Description: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene ABAT.

Products related to ABAT Gene:

83 results

OriGene sc323108 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
NCBI Accession:
NM_001127448,NP_001120920
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3320531
$507.87
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene sr416060 RNAi ABAT Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
4-Aminobutyrate Aminotransferase
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3263604
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene sr508846 RNAi ABAT Species: Rat HPLC purified
Application:
RNA Interference
Gene:
4-Aminobutyrate Aminotransferase
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3358135
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene sr300010 RNAi ABAT Species: Human HPLC purified
Application:
RNA Interference
Gene:
4-Aminobutyrate Aminotransferase
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3339806
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 8 Business Days
OriGene rg206793 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5385611
$650.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rg225860 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5385613
$650.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene tg306930 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3731816
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tg508059 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3690083
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tf508059 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3670385
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene tg711134 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3505341
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pDONR223
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-XL4
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to ABAT

  • 4-aminobutyrate aminotransferase (ABAT)
  • 4-aminobutyrate aminotransferase (abat)
  • 4-aminobutyrate--2-oxoglutarate transaminase (gabT)
  • GABA aminotransferase PLP-dependent PuuE (puuE)
  • 4-aminobutyrate aminotransferase (gabT-1)
  • 4-aminobutyrate aminotransferase (gabT-2)
  • 4-aminobutyrate aminotransferase (gabT-3)
  • 4-aminobutyrate aminotransferase (gabT)
  • 4-aminobutyrate aminotransferase (CNE01830)
  • 4-aminobutyrate aminotransferase (Mmwyl1_0047)
  • 4-aminobutyrate aminotransferase, mitochondrial (CpipJ_CPIJ008729)
  • aspartate aminotransferase family protein (KCR_RS04555)
  • 4-aminobutyrate aminotransferase (Bcenmc03_4909)
  • 4-aminobutyrate aminotransferase (Hden_0972)
  • 4-aminobutyrate aminotransferase (Dbac_2000)
  • 4-aminobutyrate aminotransferase (Mesil_2400)
  • 4-aminobutyrate aminotransferase (Trad_0121)
  • 4-aminobutyrate aminotransferase S homeolog (abat.S)
  • 4-aminobutyrate aminotransferase (Abat)
  • 9630038C02Rik
  • AI255750
  • BA0325
  • beta-AlaAT
  • cb880
  • ENSMUSG00000051226
  • fj82a01
  • GABA-AT
  • GABA-T
  • Gabaat
  • GABAT
  • Gabat
  • Gm9851
  • I54
  • L-AIBAT
  • Laibat
  • NPD009
  • PSPTO0259
  • PSPTO0301
  • PSPTO1890
  • wu:fj82a01
  • X61497

Gene-IDs for different species

Protein level used designations for ABAT

  • 4-aminobutyrate aminotransferase, mitochondrial
  • GABA-T
  • 4-aminobutyrate aminotransferase
  • (S)-3-amino-2-methylpropionate transaminase
  • 4-aminobutyrate transaminase
  • GABA aminotransferase
  • GABA transaminase
  • GABA transferase
  • gamma-amino-N-butyrate transaminase
  • GABA-AT
  • L-AIBAT
  • beta-alanine oxoglutarate aminotransferase
Other products related to ABAT such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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