ABAT (4-Aminobutyrate Aminotransferase, ABAT)
Short Description: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene ABAT.
More information related to gene ABAT.
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OriGene rc206793l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 4-Aminobutyrate Aminotransferase (ABAT)
- NCBI Accession:
- NM_000663,NP_000654
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5385618
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- 4-Aminobutyrate Aminotransferase (ABAT)
- NCBI Accession:
- NM_001127448
- Gene ID:
- 18 (Human, ABAT)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4920800
$439.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene sr300010
RNAi
ABAT
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- 4-Aminobutyrate Aminotransferase
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3339806
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to ABAT
- 4-aminobutyrate aminotransferase (ABAT)
- 4-aminobutyrate aminotransferase (abat)
- 4-aminobutyrate--2-oxoglutarate transaminase (gabT)
- GABA aminotransferase PLP-dependent PuuE (puuE)
- 4-aminobutyrate aminotransferase (gabT-1)
- 4-aminobutyrate aminotransferase (gabT-2)
- 4-aminobutyrate aminotransferase (gabT-3)
- 4-aminobutyrate aminotransferase (gabT)
- 4-aminobutyrate aminotransferase (CNE01830)
- 4-aminobutyrate aminotransferase (Mmwyl1_0047)
- 4-aminobutyrate aminotransferase, mitochondrial (CpipJ_CPIJ008729)
- aspartate aminotransferase family protein (KCR_RS04555)
- 4-aminobutyrate aminotransferase (Bcenmc03_4909)
- 4-aminobutyrate aminotransferase (Hden_0972)
- 4-aminobutyrate aminotransferase (Dbac_2000)
- 4-aminobutyrate aminotransferase (Mesil_2400)
- 4-aminobutyrate aminotransferase (Trad_0121)
- 4-aminobutyrate aminotransferase S homeolog (abat.S)
- 4-aminobutyrate aminotransferase (Abat)
- 9630038C02Rik
- AI255750
- BA0325
- beta-AlaAT
- cb880
- ENSMUSG00000051226
- fj82a01
- GABA-AT
- GABA-T
- Gabaat
- GABAT
- Gabat
- Gm9851
- I54
- L-AIBAT
- Laibat
- NPD009
- PSPTO0259
- PSPTO0301
- PSPTO1890
- wu:fj82a01
- X61497
Gene-IDs for different species
Protein level used designations for ABAT
- 4-aminobutyrate aminotransferase, mitochondrial
- GABA-T
- 4-aminobutyrate aminotransferase
- (S)-3-amino-2-methylpropionate transaminase
- 4-aminobutyrate transaminase
- GABA aminotransferase
- GABA transaminase
- GABA transferase
- gamma-amino-N-butyrate transaminase
- GABA-AT
- L-AIBAT
- beta-alanine oxoglutarate aminotransferase
Proteomics products related to ABAT Gene
Other products related to ABAT such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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