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ABAT (4-Aminobutyrate Aminotransferase, ABAT)

Short Description: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene ABAT.

Products related to ABAT Gene:

83 results :

ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735696
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735697
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5735695
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
NCBI Accession:
NM_001170978
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4492441
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
NCBI Accession:
NM_172961
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4492440
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4372540
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4372539
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4372538
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
NCBI Accession:
NM_053996
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5109639
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
NCBI Accession:
NM_172961
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5109637
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pDONR223
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-XL4
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to ABAT

  • 4-aminobutyrate aminotransferase (ABAT)
  • 4-aminobutyrate aminotransferase (abat)
  • 4-aminobutyrate--2-oxoglutarate transaminase (gabT)
  • GABA aminotransferase PLP-dependent PuuE (puuE)
  • 4-aminobutyrate aminotransferase (gabT-1)
  • 4-aminobutyrate aminotransferase (gabT-2)
  • 4-aminobutyrate aminotransferase (gabT-3)
  • 4-aminobutyrate aminotransferase (gabT)
  • 4-aminobutyrate aminotransferase (CNE01830)
  • 4-aminobutyrate aminotransferase (Mmwyl1_0047)
  • 4-aminobutyrate aminotransferase, mitochondrial (CpipJ_CPIJ008729)
  • aspartate aminotransferase family protein (KCR_RS04555)
  • 4-aminobutyrate aminotransferase (Bcenmc03_4909)
  • 4-aminobutyrate aminotransferase (Hden_0972)
  • 4-aminobutyrate aminotransferase (Dbac_2000)
  • 4-aminobutyrate aminotransferase (Mesil_2400)
  • 4-aminobutyrate aminotransferase (Trad_0121)
  • 4-aminobutyrate aminotransferase S homeolog (abat.S)
  • 4-aminobutyrate aminotransferase (Abat)
  • 9630038C02Rik
  • AI255750
  • BA0325
  • beta-AlaAT
  • cb880
  • ENSMUSG00000051226
  • fj82a01
  • GABA-AT
  • GABA-T
  • Gabaat
  • GABAT
  • Gabat
  • Gm9851
  • I54
  • L-AIBAT
  • Laibat
  • NPD009
  • PSPTO0259
  • PSPTO0301
  • PSPTO1890
  • wu:fj82a01
  • X61497

Gene-IDs for different species

Protein level used designations for ABAT

  • 4-aminobutyrate aminotransferase, mitochondrial
  • GABA-T
  • 4-aminobutyrate aminotransferase
  • (S)-3-amino-2-methylpropionate transaminase
  • 4-aminobutyrate transaminase
  • GABA aminotransferase
  • GABA transaminase
  • GABA transferase
  • gamma-amino-N-butyrate transaminase
  • GABA-AT
  • L-AIBAT
  • beta-alanine oxoglutarate aminotransferase
Other products related to ABAT such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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