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ABAT (4-Aminobutyrate Aminotransferase, ABAT)

Short Description: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene ABAT.

Products related to ABAT Gene:

83 results

OriGene tl508059 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3520673
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene kn500597 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3244867
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 21 Business Days
OriGene kn406793 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
4-Aminobutyrate Aminotransferase (ABAT)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3244866
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 21 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • ProteoGenix
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pDONR223
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-XL4
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to ABAT

  • 4-aminobutyrate aminotransferase (ABAT)
  • 4-aminobutyrate aminotransferase (abat)
  • 4-aminobutyrate--2-oxoglutarate transaminase (gabT)
  • GABA aminotransferase PLP-dependent PuuE (puuE)
  • 4-aminobutyrate aminotransferase (gabT-1)
  • 4-aminobutyrate aminotransferase (gabT-2)
  • 4-aminobutyrate aminotransferase (gabT-3)
  • 4-aminobutyrate aminotransferase (gabT)
  • 4-aminobutyrate aminotransferase (CNE01830)
  • 4-aminobutyrate aminotransferase (Mmwyl1_0047)
  • 4-aminobutyrate aminotransferase, mitochondrial (CpipJ_CPIJ008729)
  • aspartate aminotransferase family protein (KCR_RS04555)
  • 4-aminobutyrate aminotransferase (Bcenmc03_4909)
  • 4-aminobutyrate aminotransferase (Hden_0972)
  • 4-aminobutyrate aminotransferase (Dbac_2000)
  • 4-aminobutyrate aminotransferase (Mesil_2400)
  • 4-aminobutyrate aminotransferase (Trad_0121)
  • 4-aminobutyrate aminotransferase S homeolog (abat.S)
  • 4-aminobutyrate aminotransferase (Abat)
  • 9630038C02Rik
  • AI255750
  • BA0325
  • beta-AlaAT
  • cb880
  • ENSMUSG00000051226
  • fj82a01
  • GABA-AT
  • GABA-T
  • Gabaat
  • GABAT
  • Gabat
  • Gm9851
  • I54
  • L-AIBAT
  • Laibat
  • NPD009
  • PSPTO0259
  • PSPTO0301
  • PSPTO1890
  • wu:fj82a01
  • X61497

Gene-IDs for different species

Protein level used designations for ABAT

  • 4-aminobutyrate aminotransferase, mitochondrial
  • GABA-T
  • 4-aminobutyrate aminotransferase
  • (S)-3-amino-2-methylpropionate transaminase
  • 4-aminobutyrate transaminase
  • GABA aminotransferase
  • GABA transaminase
  • GABA transferase
  • gamma-amino-N-butyrate transaminase
  • GABA-AT
  • L-AIBAT
  • beta-alanine oxoglutarate aminotransferase
Other products related to ABAT such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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