ALPL (Alkaline Phosphatase, Liver/bone/kidney, ALPL)
Short Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
More information related to gene ALPL.
More information related to gene ALPL.
Products related to ALPL Gene:
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OriGene sr300174
RNAi
ALPL
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3339969
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5324075
$215.19
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5324704
$215.19
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 19 Business Days
Synonyms and alternative names related to ALPL
- alkaline phosphatase, liver/bone/kidney (ALPL)
- alkaline phosphatase, liver/bone/kidney L homeolog (alpl.L)
- alkaline phosphatase, liver/bone/kidney (Alpl)
- alkaline phosphatase, intestinal, gene 2 (alpi.2)
- Akp-2
- Akp2
- ALP
- alpl
- AP-TNAP
- APTNAP
- HOPS
- iap
- PHOA
- TNAP
- TNS-AP
- TNSALP
Gene-IDs for different species
Protein level used designations for ALPL
- alkaline phosphatase liver/bone/kidney isozyme
- alkaline phosphatase, tissue-nonspecific isozyme
- alkaline phosphomonoesterase
- glycerophosphatase
- liver/bone/kidney-type alkaline phosphatase
- tissue-nonspecific ALP
- tissue non-specific alkaline phosphatase
- tissue-nonspecific alkaline phosphatase
- AP-TNAP
- TNSALP
- alkaline phosphatase tissue non-specific isoform
- liver/bone/kidney isozyme
- alkaline phosphatase 2, liver
- Tissue-nonspecific ALP alkaline phosphatase
- alkaline phosphatase, liver/bone/kidney
- alkaline phosphatase, tissue-nonspecific isozyme-like
Proteomics products related to ALPL Gene
Other products related to ALPL such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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