ALPL (Alkaline Phosphatase, Liver/bone/kidney, ALPL)
Short Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization\; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
More information related to gene ALPL.
More information related to gene ALPL.
Products related to ALPL Gene:
Recommended next Filters:
73 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- NCBI Accession:
- NM_007431
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- NCBI Accession:
- NM_007431
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- NCBI Accession:
- NM_013059
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- NCBI Accession:
- NM_007431
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- NCBI Accession:
- NM_000478
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- NCBI Accession:
- NM_007431
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Alkaline Phosphatase, Liver/bone/kidney (ALPL)
- NCBI Accession:
- NM_007431
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
Synonyms and alternative names related to ALPL
- alkaline phosphatase, liver/bone/kidney L homeolog (alpl.L)
- alkaline phosphatase, liver/bone/kidney (ALPL)
- alkaline phosphatase, intestinal, gene 2 (alpi.2)
- alkaline phosphatase, liver/bone/kidney pseudogene (LOC100031702)
- alkaline phosphatase, liver/bone/kidney (Alpl)
- Akp-2
- Akp2
- ALP
- alpl
- AP-TNAP
- APTNAP
- HOPS
- iap
- PHOA
- TNAP
- TNS-AP
- TNSALP
Gene-IDs for different species
Protein level used designations for ALPL
- tissue-nonspecific alkaline phosphatase
- alkaline phosphatase, tissue-nonspecific isozyme
- tissue non-specific alkaline phosphatase
- alkaline phosphatase, liver/bone/kidney
- alkaline phosphatase, tissue-nonspecific isozyme-like
- alkaline phosphatase liver/bone/kidney isozyme
- alkaline phosphomonoesterase
- glycerophosphatase
- liver/bone/kidney-type alkaline phosphatase
- tissue-nonspecific ALP
- alkaline phosphatase 2, liver
- AP-TNAP
- TNSALP
- Tissue-nonspecific ALP alkaline phosphatase
- alkaline phosphatase tissue non-specific isoform
- liver/bone/kidney isozyme
Proteomics products related to ALPL Gene
Other products related to ALPL such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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