APEX1 (Apurinic/Apyrimidinic Endonuclease 1, APEX1)
Short Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene\; all encode the same protein. [provided by RefSeq, Jul 2008].
More information related to gene APEX1.
More information related to gene APEX1.
Products related to APEX1 Gene:
Recommended next Filters:
80 results
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
- NCBI Accession:
- NM_001039138
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5104530
$1,511.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
- NCBI Accession:
- NM_001641
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5104528
$1,511.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
- NCBI Accession:
- NM_024148
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5104532
$1,511.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
- NCBI Accession:
- NM_024148
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5219791
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
- NCBI Accession:
- NM_001039138
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5219789
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
- NCBI Accession:
- NM_001641
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5219787
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5316378
$223.79
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 17 Business Days
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5312109
$223.79
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 17 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Apurinic/Apyrimidinic Endonuclease 1 (APEX1)
- NCBI Accession:
- NM_080649
- Gene ID:
- 328 (Human, APEX1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4920676
$199.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 6 Business Days
OriGene rc232466
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1)
- NCBI Accession:
- NM_001244249,NP_001231178
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5376894
$286.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Will be delivered in 21 Business Days
Synonyms and alternative names related to APEX1
- apurinic/apyrimidinic endodeoxyribonuclease 1 (APEX1)
- APEX nuclease (multifunctional DNA repair enzyme) 1 (apex1)
- APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog (apex1.L)
- DNA-(apurinic or apyrimidinic site) lyase (CNG03640)
- DNA-(apurinic or apyrimidinic site) lyase (CNH01280)
- DNA-(apurinic or apyrimidinic site) lyase (nth)
- DNA-(apurinic or apyrimidinic site) lyase (Spirs_4119)
- DNA-(apurinic or apyrimidinic site) lyase (Palpr_0103)
- apurinic/apyrimidinic endodeoxyribonuclease 1 (Apex1)
- apurinic/apyrimidinic endonuclease 1 (Apex1)
- APE
- APE1
- APEN
- APEX
- Apex
- apex1
- apex1a
- APX
- BAP1
- HAP1
- hm:zehn1532
- MGC76280
- MGC78928
- MGC79645
- REF-1
- Ref-1
- REF1
- wu:fc13d11
- zgc:66204
Gene-IDs for different species
Protein level used designations for APEX1
- DNA-(apurinic or apyrimidinic site) lyase
- APEX nuclease 1
- APEX nuclease (multifunctional DNA repair enzyme) 1
- AP endonuclease class I
- AP lyase
- apurinic-apyrimidinic endonuclease 1
- apurinic/apyrimidinic (abasic) endonuclease
- deoxyribonuclease (apurinic or apyrimidinic)
- protein REF-1
- redox factor-1
- AP endonuclease 1
- APEN
- apurinic/apyrimidinic endonuclease 1
- apurinic/apyrimidinic endonuclease
- zap1
- Apurinic-apyrimidinic endonuclease 1
- Redox factor-1
- APEX nuclease
Proteomics products related to APEX1 Gene
Other products related to APEX1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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