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APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2, APEX2)

Short Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012].
More information related to gene APEX2.

Products related to APEX2 Gene:

58 results

ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Gene ID:
27301 (Human, APEX2)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5314915
$223.79
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 17 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001271748
Gene ID:
27301 (Human, APEX2)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4920675
$319.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 6 Business Days
OriGene rc200320 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_014481,NP_055296
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5376946
$477.18
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
OriGene sc122813 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_014481,NP_055296
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3388237
$478.17
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 8 Business Days
OriGene rc232544 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001271748,NP_001258677
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5376947
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene sr416495 RNAi APEX2 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3264032
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene sr502559 RNAi APEX2 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3352733
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Will be delivered in 16 Business Days
OriGene sr309077 RNAi APEX2 Species: Human HPLC purified
Application:
RNA Interference
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3285114
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 8 Business Days
OriGene rn202845 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
NCBI Accession:
NM_001079892,NP_001073361
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3375991
$523.71
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
OriGene rg200320 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5376944
$675.18
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 21 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to APEX2

  • apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 (apex2)
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (apex2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog (apex2.L)
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2)
  • apurinic/apyrimidinic endonuclease 2 (Apex2)
  • apurinic/apyrimidinic endodeoxyribonuclease 2 (Apex2)
  • APE2
  • ape2
  • APEXL2
  • apexl2
  • C430040P13Rik
  • XTH2
  • xth2
  • zgc:55889

Gene-IDs for different species

Protein level used designations for APEX2

  • AP endonuclease 2
  • AP endonuclease XTH2
  • DNA-(apurinic or apyrimidinic site) lyase 2
  • apurinic/apyrimidinic endonuclease-like 2
  • APEX nuclease 2
  • apurinic-apyrimidinic endonuclease 2
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2
  • DNA-(apurinic or apyrimidinic site) lyase 2-like
Other products related to APEX2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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