CD130/gp130 (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor), IL6ST)
Short Description: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2010].
More information related to gene CD130/gp130.
More information related to gene CD130/gp130.
Products related to CD130/gp130 Gene:
Recommended next Filters:
62 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- NCBI Accession:
- NM_010560
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- NCBI Accession:
- NM_010560
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- NCBI Accession:
- NM_001008725
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- NCBI Accession:
- NM_175767
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- NCBI Accession:
- NM_001008725
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- NCBI Accession:
- NM_010560
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- NCBI Accession:
- NM_175767
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST)
- NCBI Accession:
- NM_010560
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
Synonyms and alternative names related to CD130/gp130
- interleukin 6 signal transducer (IL6ST)
- interleukin 6 signal transducer (Il6st)
- interleukin 6 signal transducer (il6st)
- 5133400A03Rik
- AA389424
- Ac1055
- BB405851
- CD130
- CDW130
- D13Ertd699e
- GP130
- gp130
- Gp130
- IL-6
- IL-6RB
- Il-6rb
Gene-IDs for different species
Protein level used designations for CD130/gp130
- CD130 antigen
- IL-6 receptor subunit beta
- IL-6R subunit beta
- gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
- interleukin receptor beta chain
- interleukin-6 receptor subunit beta
- membrane glycoprotein 130
- membrane glycoprotein gp130
- oncostatin-M receptor subunit alpha
- IL-6R-beta
- IL-6RB
- interleukin-6 signal transducer
- interleukin 6 signal transducer
- glycoprotein 130
- LOW QUALITY PROTEIN: interleukin-6 receptor subunit beta
- interleukin 6 signal transducer (gp130, oncostatin M receptor)
- interleukin 6 signal transducer receptor
Proteomics products related to CD130/gp130 Gene
Other products related to CD130/gp130 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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