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CD45 (Protein tyrosine Phosphatase, Receptor Type, C, PTPRC)

Short Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012].
More information related to gene CD45.

Products related to CD45 Gene:

86 results :

Human PTPRC ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738838
Datasheet
Catalog No. ABIN5738838
Type:
ORF
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
Species:
Human
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Insert length:
3921 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse PTPRC CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_001111316
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231034
Datasheet
Catalog No. ABIN5231034
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_001111316
Species:
Mouse
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptprc
Format:
Viral Particles
Storage:
-80 °C
Human PTPRC CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_080923
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231032
Datasheet
Catalog No. ABIN5231032
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_080923
Species:
Human
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PTPRC
Format:
Viral Particles
Storage:
-80 °C
Rat PTPRC CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_138507
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231036
Datasheet
Catalog No. ABIN5231036
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_138507
Species:
Rat
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptprc
Format:
Viral Particles
Storage:
-80 °C
Mouse PTPRC cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_001111316
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4453965
Datasheet
Catalog No. ABIN4453965
Type:
cDNA
Application:
Protein Expression
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_001111316
Species:
Mouse
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Insert length:
3876 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PTPRC cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_011210
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4453966
Datasheet
Catalog No. ABIN4453966
Type:
cDNA
Application:
Protein Expression
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_011210
Species:
Mouse
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Insert length:
3459 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PTPRC CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_001111316
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115680
Datasheet
Catalog No. ABIN5115680
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_001111316
Species:
Mouse
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptprc
Format:
Viral Particles
Storage:
-80 °C
Rat PTPRC CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_138507
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115682
Datasheet
Catalog No. ABIN5115682
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_138507
Species:
Rat
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptprc
Format:
Viral Particles
Storage:
-80 °C
Human PTPRC CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_080923
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115678
Datasheet
Catalog No. ABIN5115678
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_080923
Species:
Human
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PTPRC
Format:
Viral Particles
Storage:
-80 °C
Mouse PTPRC ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_001111316
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738839
Datasheet
Catalog No. ABIN5738839
Type:
ORF
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
NCBI Accession:
NM_001111316
Species:
Mouse
Synonyms:
PTPRC, ptprc, LOC100074271, Ptprc
Insert length:
3876 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Rat
    • Human
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • Myc-DYKDDDDK Tag
    • GFP tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-Neo
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CD45

  • protein tyrosine phosphatase, receptor type C (PTPRC)
  • protein tyrosine phosphatase, receptor type, C (ptprc)
  • receptor-type tyrosine-protein phosphatase C (LOC100074271)
  • protein tyrosine phosphatase, receptor type, C (Ptprc)
  • B220
  • CD45
  • Cd45
  • cd45
  • CD45R
  • GP180
  • L-CA
  • LCA
  • Lca
  • loc
  • Ly-5
  • LY5
  • Lyt-4
  • PTPRC
  • RT7
  • si:dkeyp-47c5.1
  • T200

Gene-IDs for different species

Protein level used designations for CD45

  • receptor-type tyrosine-protein phosphatase C
  • leukocyte common antigen, CD45
  • protein tyrosine phosphatase, receptor type, C
  • CD45 antigen
  • leukocyte common antigen
  • receptor-type tyrosine-protein phosphatase C-like
  • T200 glycoprotein
  • T200 leukocyte common antigen
  • protein tyrosine phosphatase, receptor type, c polypeptide
  • lymphocyte antigen 5
  • lymphocyte common antigen
  • Protein tyrosine phosphatase, receptor-type, c polypeptide
  • leucocyte common antigen
  • leukocyte common antigen A
  • leukocyte common antigen B
  • membrane tyrosine phosphatase
Other products related to CD45 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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