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CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa, CPSF4)

Short Description: Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
More information related to gene CPSF4.

Products related to CPSF4 Gene:

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72 results

Mouse CPSF4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc206876 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3297277
$148.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Mouse CPSF4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc226525 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_001291249,NP_001278178
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3297279
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse CPSF4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc226532 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_001291248,NP_001278177
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3297280
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse CPSF4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc209957 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_178576,NP_848671
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3297278
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Rat CPSF4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rn209914 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_001012351,NP_001012351
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3297281
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Mouse CPSF4 CRISPR gRNA + Cas9 in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene kn503779 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3251711
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human CPSF4 CRISPR gRNA + Cas9 in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene kn400532 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3251710
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Rat CPSF4 siRNA Oligo
OriGene sr509627 RNAi CPSF4 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3358796
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human CPSF4 cDNA Clone in Mammalian Expression Vector
OriGene sc320181 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_001081559,NP_001075028
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3319725
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Human CPSF4 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene sc312726 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4)
NCBI Accession:
NM_006693,NP_006684
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3289094
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL5
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CPSF4

  • cleavage and polyadenylation specific factor 4 (CPSF4)
  • cleavage and polyadenylation specific factor 4, 30kDa (Cpsf4)
  • cleavage and polyadenylation specific factor 4 (LOC733099)
  • cleavage and polyadenylation specific factor 4 (LOC100360200)
  • cleavage and polyadenylation specific factor 4 S homeolog (cpsf4.S)
  • cleavage and polyadenylation specific factor 4 (cpsf4)
  • cleavage and polyadenylation specific factor 4 (Cpsf4)
  • 30kDa
  • C79664
  • cpsf30
  • CPSF30
  • nar
  • NAR
  • neb1
  • NEB1

Gene-IDs for different species

Protein level used designations for CPSF4

  • no arches
  • GLEAN_10339
  • cleavage and polyadenylation specific factor 4
  • cleavage and polyadenylation specificity factor subunit 4
  • cleavage and polyadenylation specific factor 4, 30kDa
  • CPSF 30 kDa subunit
  • cleavage and polyadenylation specific factor 4, 30kD subunit
  • cleavage and polyadenylation specificity factor 30 kDa subunit
  • clipper homolog
  • clipper/CPSF 30K
  • musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit
  • NS1 effector domain-binding protein 1
  • cleavage-polyadenylation specificity factor, 30kD
  • neb-1
  • no arches homolog
  • no arches-like zinc finger protein
  • cleavage-polyadenylation specificity factor, 30 kD
Other products related to CPSF4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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