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CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa, CPSF4)

Short Description: Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
More information related to gene CPSF4.

Products related to CPSF4 Gene:

72 results

OriGene sr403480 RNAi CPSF4 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3277491
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr307433 RNAi CPSF4 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Cleavage and Polyadenylation Specific Factor 4, 30kDa
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3283475
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL5
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to CPSF4

  • cleavage and polyadenylation specific factor 4 (CPSF4)
  • cleavage and polyadenylation specific factor 4, 30kDa (Cpsf4)
  • cleavage and polyadenylation specific factor 4 (LOC733099)
  • cleavage and polyadenylation specific factor 4 (LOC100360200)
  • cleavage and polyadenylation specific factor 4 S homeolog (cpsf4.S)
  • cleavage and polyadenylation specific factor 4 (cpsf4)
  • cleavage and polyadenylation specific factor 4 (Cpsf4)
  • 30kDa
  • C79664
  • cpsf30
  • CPSF30
  • nar
  • NAR
  • neb1
  • NEB1

Gene-IDs for different species

Protein level used designations for CPSF4

  • no arches
  • GLEAN_10339
  • cleavage and polyadenylation specific factor 4
  • cleavage and polyadenylation specificity factor subunit 4
  • cleavage and polyadenylation specific factor 4, 30kDa
  • CPSF 30 kDa subunit
  • cleavage and polyadenylation specific factor 4, 30kD subunit
  • cleavage and polyadenylation specificity factor 30 kDa subunit
  • clipper homolog
  • clipper/CPSF 30K
  • musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit
  • NS1 effector domain-binding protein 1
  • cleavage-polyadenylation specificity factor, 30kD
  • neb-1
  • no arches homolog
  • no arches-like zinc finger protein
  • cleavage-polyadenylation specificity factor, 30 kD
Other products related to CPSF4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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