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CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6, CYP2D6)

Short Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene CYP2D6.

Products related to CYP2D6 Gene:

31 results

OriGene sr301106 RNAi CYP2D6 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3340894
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pCMV6-Entry
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pCMV6-XL5
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • gRNA
    • shRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to CYP2D6

  • cytochrome P450 family 2 subfamily D member 6 (CYP2D6)
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6)
  • cytochrome 2D6 (CYP2D6)
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b)
  • cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S)
  • cytochrome P450 family 2 subfamily D member 6 (cyp2d6)
  • cytochrome P450 2D6 (CYP2D6)
  • cytochrome P450 2D6-like (LOC100988273)
  • CPD6
  • CYP2D
  • cyp2d2
  • CYP2D6
  • cyp2d6-a
  • CYP2D7AP
  • CYP2D7BP
  • CYP2D7P2
  • CYP2D8P2
  • CYP2D42
  • CYP2DL1
  • CYPIID6
  • MGC64445
  • P450-DB1
  • P450C2D
  • P450DB1

Gene-IDs for different species

Protein level used designations for CYP2D6

  • cytochrome P450 2D6
  • cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2
  • cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2
  • cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2
  • cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2
  • cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6
  • cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1
  • cytochrome P450-DB1
  • debrisoquine 4-hydroxylase
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • xenobiotic monooxygenase
  • CYPIID6
  • cytochrome P450 CYP2D42
  • cytochrome P450, family 2, subfamily D, polypeptide 6
  • cytochrome P450 2D6-like
Other products related to CYP2D6 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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