Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

CYP2D6 (Cytochrome P450, Family 2, Subfamily D, Polypeptide 6, CYP2D6)

Short Description: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene CYP2D6.

Products related to CYP2D6 Gene:

31 results :

cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4487656
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
NCBI Accession:
NM_000106
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739327
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
NCBI Accession:
NG_005574
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231956
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
NCBI Accession:
NG_000853
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231958
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
NCBI Accession:
NM_000106
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5231954
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
NCBI Accession:
NG_000853
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116604
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
NCBI Accession:
NG_005574
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116602
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
NCBI Accession:
NM_000106
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5116600
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4829847
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4700718
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pCMV6-Entry
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pCMV6-XL5
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • gRNA
    • shRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • PGK Promoter
    • SFFV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to CYP2D6

  • cytochrome P450 family 2 subfamily D member 6 (CYP2D6)
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6)
  • cytochrome 2D6 (CYP2D6)
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b)
  • cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S)
  • cytochrome P450 family 2 subfamily D member 6 (cyp2d6)
  • cytochrome P450 2D6 (CYP2D6)
  • cytochrome P450 2D6-like (LOC100988273)
  • CPD6
  • CYP2D
  • cyp2d2
  • CYP2D6
  • cyp2d6-a
  • CYP2D7AP
  • CYP2D7BP
  • CYP2D7P2
  • CYP2D8P2
  • CYP2D42
  • CYP2DL1
  • CYPIID6
  • MGC64445
  • P450-DB1
  • P450C2D
  • P450DB1

Gene-IDs for different species

Protein level used designations for CYP2D6

  • cytochrome P450 2D6
  • cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2
  • cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2
  • cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2
  • cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2
  • cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6
  • cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1
  • cytochrome P450-DB1
  • debrisoquine 4-hydroxylase
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • xenobiotic monooxygenase
  • CYPIID6
  • cytochrome P450 CYP2D42
  • cytochrome P450, family 2, subfamily D, polypeptide 6
  • cytochrome P450 2D6-like
Other products related to CYP2D6 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
Support