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DCLK1 (Doublecortin-Like Kinase 1, DCLK1)

Short Description: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010].
More information related to gene DCLK1.

Products related to DCLK1 Gene:

91 results

cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_001195538
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4408135
$2,360.10
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_001195538
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4640832
$2,360.10
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 31 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_001195430
Gene ID:
9201 (Human, DCLK1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4930710
$99.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 8 Business Days
OriGene mc208367 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_001195540,NP_001182469
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322898
$163.35
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 16 Business Days
OriGene rn215709 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_021584,NP_067595
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322904
$163.35
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 16 Business Days
OriGene rr215709 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5399230
$163.35
Plus shipping costs $50.00
10 μg
Shipping to: United States
Will be delivered in 16 Business Days
OriGene rc230914 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_001195430,NP_001182359
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5399226
$237.60
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 10 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_001195415
Gene ID:
9201 (Human, DCLK1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4930711
$349.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 8 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_001195416
Gene ID:
9201 (Human, DCLK1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4930712
$359.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 8 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Doublecortin-Like Kinase 1 (DCLK1)
NCBI Accession:
NM_004734
Gene ID:
9201 (Human, DCLK1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4940143
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 6 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRFP-C-RS
    • pRS
    • pCas-Guide
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to DCLK1

  • doublecortin like kinase 1 (DCLK1)
  • doublecortin-like kinase 1a (dclk1a)
  • serine/threonine-protein kinase DCLK1 (LOC587664)
  • doublecortin-like kinase 2 (dclk2)
  • serine/threonine-protein kinase DCLK1 (LOC100539645)
  • doublecortin-like kinase 1 (Dclk1)
  • doublecortin-like kinase 1 (DCLK1)
  • doublecortin like kinase 1 (Dclk1)
  • 1700113D08Rik
  • 2810480F11Rik
  • AI836758
  • Ania4
  • CL1
  • Click-I
  • CLICK1
  • Cpg16
  • DCAMKL1
  • dcamkl1
  • Dcamkl1
  • DCDC3A
  • Dcl
  • DCLK
  • Dclk
  • DCLK1
  • dclk1
  • MGC145348
  • mKIAA0369
  • wu:fc51f11
  • zgc:153709

Gene-IDs for different species

Protein level used designations for DCLK1

  • doublecortin-like kinase 1
  • doublecortin and CaM kinase-like 1
  • doublecortin and calcium/calmodulin-dependent protein kinase-like 1
  • serine/threonine-protein kinase DCLK1
  • doublecortin-like kinase 2
  • serine/threonine-protein kinase DCLK1-like
  • doublecortin domain-containing protein 3A
  • doublecortin-like and CAM kinase-like 1
  • CLICK-I beta
  • double cortin and calcium/calmodulin-dependent protein kinase-like 1
Other products related to DCLK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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