DDB1 (Damage Specific DNA Binding Protein 1, DDB1)
Short Description: The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012].
More information related to gene DDB1.
More information related to gene DDB1.
Products related to DDB1 Gene:
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38 results
OriGene sc118946
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923,NP_001914
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3383600
$983.07
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923
- Gene ID:
- 1642 (Human, DDB1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4940125
$549.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene rc208372
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923,NP_001914
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5399311
$1,473.12
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc208372l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923,NP_001914
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5399313
$1,770.12
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg208372
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5399310
$1,671.12
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rr217500
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5399312
$1,080.09
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc208372l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923,NP_001914
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5399314
$1,770.12
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr301160
RNAi
DDB1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Damage Specific DNA Binding Protein 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3340948
$435.60
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to DDB1
- damage specific DNA binding protein 1 (DDB1)
- damage-specific DNA binding protein 1, 127kDa (ddb1)
- DNA damage-binding protein 1 (LOC100187356)
- damage specific DNA binding protein 1 (Ddb1)
- damage-specific DNA binding protein 1 (Ddb1)
- DNA damage-binding protein 1 (ddb-1)
- 127kDa
- AA408517
- DDB1
- ddb1
- DDBA
- ddba
- p127-Ddb1
- UV-DDB1
- uv-ddb1
- XAP1
- xap1
- XPCE
- xpce
- XPE
- xpe
- XPE-BF
- xpe-bf
Gene-IDs for different species
Protein level used designations for DDB1
- DDB p127 subunit
- DNA damage-binding protein 1
- DNA damage-binding protein a
- HBV X-associated protein 1
- UV-DDB 1
- UV-damaged DNA-binding factor
- UV-damaged DNA-binding protein 1
- XAP-1
- XPE-binding factor
- xeroderma pigmentosum group E-complementing protein
- damage-specific DNA-binding protein 1
- damage-specific DNA binding protein 1, 127kDa
- DNA damage-binding protein 1-like
- DNA repair protein
- damage-specific DNA-binding protein, DNA repair
- damaged-DNA recognition protein 1
- damage specific DNA binding protein 1
Proteomics products related to DDB1 Gene
Other products related to DDB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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