DDB1 (Damage Specific DNA Binding Protein 1, DDB1)
Short Description: The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients. The protein encoded by this gene also functions as an adaptor molecule for the cullin 4 (CUL4) ubiquitin E3 ligase complex by facilitating the binding of substrates to this complex and the ubiquitination of proteins. [provided by RefSeq, May 2012].
More information related to gene DDB1.
More information related to gene DDB1.
Products related to DDB1 Gene:
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38 results
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_015735
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
Catalog No. ABIN4408204
$2,360.10
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
Catalog No. ABIN4422602
$1,855.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
Catalog No. ABIN4631159
$1,855.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
Catalog No. ABIN4487689
$1,653.36
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_015735
- Species:
- Mouse
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
Catalog No. ABIN4640901
$2,360.10
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- NCBI Accession:
- NM_001923
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4700852
$1,855.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 32 Business Days
OriGene rc208372l2v
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN6406171
$2,017.62
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 27 Business Days
OriGene rc208372l1v
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN6406170
$2,017.62
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to:
United States
Delivery in 21 to 27 Business Days
OriGene tg313538
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3738376
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg516223
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Damage Specific DNA Binding Protein 1 (DDB1)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3698212
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to DDB1
- damage specific DNA binding protein 1 (DDB1)
- damage-specific DNA binding protein 1, 127kDa (ddb1)
- DNA damage-binding protein 1 (LOC100187356)
- damage specific DNA binding protein 1 (Ddb1)
- damage-specific DNA binding protein 1 (Ddb1)
- DNA damage-binding protein 1 (ddb-1)
- 127kDa
- AA408517
- DDB1
- ddb1
- DDBA
- ddba
- p127-Ddb1
- UV-DDB1
- uv-ddb1
- XAP1
- xap1
- XPCE
- xpce
- XPE
- xpe
- XPE-BF
- xpe-bf
Gene-IDs for different species
Protein level used designations for DDB1
- DDB p127 subunit
- DNA damage-binding protein 1
- DNA damage-binding protein a
- HBV X-associated protein 1
- UV-DDB 1
- UV-damaged DNA-binding factor
- UV-damaged DNA-binding protein 1
- XAP-1
- XPE-binding factor
- xeroderma pigmentosum group E-complementing protein
- damage-specific DNA-binding protein 1
- damage-specific DNA binding protein 1, 127kDa
- DNA damage-binding protein 1-like
- DNA repair protein
- damage-specific DNA-binding protein, DNA repair
- damaged-DNA recognition protein 1
- damage specific DNA binding protein 1
Proteomics products related to DDB1 Gene
Other products related to DDB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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