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DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A, DYRK1A)

Short Description: This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008].
More information related to gene DYRK1A.

Products related to DYRK1A Gene:

70 results :

Rat DYRK1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_012791
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233492
Datasheet
Catalog No. ABIN5233492
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_012791
Species:
Rat
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dyrk1a
Format:
Viral Particles
Storage:
-80 °C
Mouse DYRK1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_007890
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233490
Datasheet
Catalog No. ABIN5233490
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_007890
Species:
Mouse
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dyrk1a
Format:
Viral Particles
Storage:
-80 °C
Human DYRK1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_130436
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233488
Datasheet
Catalog No. ABIN5233488
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_130436
Species:
Human
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DYRK1A
Format:
Viral Particles
Storage:
-80 °C
Rat DYRK1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_012791
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118132
Datasheet
Catalog No. ABIN5118132
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_012791
Species:
Rat
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dyrk1a
Format:
Viral Particles
Storage:
-80 °C
Mouse DYRK1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_007890
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118130
Datasheet
Catalog No. ABIN5118130
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_007890
Species:
Mouse
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dyrk1a
Format:
Viral Particles
Storage:
-80 °C
Human DYRK1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_130436
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118128
Datasheet
Catalog No. ABIN5118128
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_130436
Species:
Human
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DYRK1A
Format:
Viral Particles
Storage:
-80 °C
Mouse DYRK1A ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_007890
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740158
Datasheet
Catalog No. ABIN5740158
Type:
ORF
Application:
Cloning
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_007890
Species:
Mouse
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Insert length:
2292 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse DYRK1A ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_001113389
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740159
Datasheet
Catalog No. ABIN5740159
Type:
ORF
Application:
Cloning
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_001113389
Species:
Mouse
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Insert length:
2292 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat DYRK1A ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_012791
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740160
Datasheet
Catalog No. ABIN5740160
Type:
ORF
Application:
Cloning
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_012791
Species:
Rat
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Insert length:
2292 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat DYRK1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_012791
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5233491
Datasheet
Catalog No. ABIN5233491
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A)
NCBI Accession:
NM_012791
Species:
Rat
Synonyms:
DYRK1A, dyrk1a, Dyrk1a, dyrk1a.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Dyrk1a
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-XL4
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to DYRK1A

  • dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A)
  • dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (dyrk1a)
  • dual specificity tyrosine phosphorylation regulated kinase 1A (dyrk1a)
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a (Dyrk1a)
  • dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a)
  • dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog (dyrk1a.S)
  • 2310043O08Rik
  • D16Ertd272e
  • D16Ertd493e
  • dyrk
  • DYRK
  • Dyrk
  • dyrk1
  • DYRK1
  • DYRK1A
  • ENSMUSG00000074897
  • Gm10783
  • hp86
  • HP86
  • mmb
  • mnb
  • MNB
  • mnbh
  • MNBH
  • Mnbh
  • Mp86
  • MRD7
  • PSK47

Gene-IDs for different species

Protein level used designations for DYRK1A

  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
  • dual specificity tyrosine-phosphorylation-regulated kinase 1A
  • minibrain
  • protein kinase minibrain homolog
  • dual specificity tyrosine-phosphorylation-regulated kinase 1A-like
  • MNB/DYRK protein kinase
  • dual specificity YAK1-related kinase
  • hMNB
  • mnb protein kinase homolog hp86
  • serine/threonine kinase MNB
  • serine/threonine-specific protein kinase
  • Dual Specificity Yak1-related kinase
  • MNBH
  • RP86
  • minibrain protein kinase
  • Protein kinase minibrain homolog
Other products related to DYRK1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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