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Dystroglycan (Dystroglycan 1, DAG1)

Short Description: Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010].
More information related to gene Dystroglycan.

Products related to Dystroglycan Gene:

82 results

OriGene mc229122 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_001276485,NP_001263414
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3298233
$891.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc222410 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_010017,NP_034147
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3298230
$891.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
OriGene mc229123 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_001276486,NP_001263415
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3298234
$891.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rn217306 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_053697,NP_446149
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3298238
$891.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc229125 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_001276493,NP_001263422
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3298236
$891.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn304265 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3252616
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 10 to 13 Business Days
OriGene kn401121 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3252615
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sr421019 RNAi DAG1 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Dystroglycan 1
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3347887
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sc117393 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_004393,NP_004384
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3377678
$811.80
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc329202 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_001177635,NP_001171106
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3389214
$1,658.25
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 36 to 37 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-XL4
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • U6 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to Dystroglycan

  • DystroGlycaN (dgn-1)
  • dystroglycan 1 L homeolog (dag1.L)
  • DystroGlycaN (dgn-2)
  • DystroGlycaN (dgn-3)
  • dystroglycan 1 (DAG1)
  • dystroglycan 1 S homeolog (dag1.S)
  • dystroglycan 1 (Dag1)
  • dystroglycan 1 (dag1)
  • Dystroglycan (Dg)
  • dystroglycan (LOC408826)
  • clusterin (Clu)
  • lymphocyte antigen 6 complex (Ly6)
  • 156DAG
  • 156dag
  • A3a
  • a3a
  • AGRNR
  • agrnr
  • Ala-1
  • APOJ
  • atu
  • CG18250
  • CLI
  • CT41273
  • D9Wsu13e
  • DAG
  • dag
  • dag1
  • DAG1
  • dg
  • DG
  • dgn
  • DmDG
  • Dmel\\CG18250
  • Dp71
  • Dp427
  • dys
  • GB14967
  • H9/25
  • LOC398500
  • Ly-6
  • Ly-27
  • Ly27
  • MDDGC7
  • MDDGC9
  • MGC53537
  • RAB7
  • RATTRPM2B
  • SGP-2
  • SGP2
  • SP-40
  • SP40
  • TRPM-2
  • Trpm2
  • TRPM2B
  • Trpmb
  • wu:fb83d06
  • wu:fi25f06
  • wu:fi37b08
  • zgc:109786

Gene-IDs for different species

Protein level used designations for Dystroglycan

  • DystroGlycaN family member (dgn-1)
  • dystroglycan
  • DystroGlycaN family member (dgn-2)
  • DystroGlycaN family member (dgn-3)
  • dystrophin-associated glycoprotein 1
  • dystroglycan 1
  • dystroglycan 1 (dystrophin-associated glycoprotein 1)
  • RAB7, member RAS oncogene family
  • glycine cleavage system T-protein
  • alpha-dystroglycan
  • beta-dystroglycan
  • dystrophin associated glycoprotein 1
  • CG18250-PA
  • CG18250-PB
  • CG18250-PC
  • CG18250-PD
  • Dg-PA
  • Dg-PB
  • Dg-PC
  • Dg-PD
  • atsugari
  • dystroglycan-like
  • dimeric acid glycoprotein
  • sulfated glycoprotein 2
  • testosterone repressed prostate message 2
  • testosterone-repressed prostate message
  • testostrone-repressed prostate message 2
  • dystrophin-associated glycoprote
Other products related to Dystroglycan such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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