Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

Dystroglycan (Dystroglycan 1, DAG1)

Short Description: Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010].
More information related to gene Dystroglycan.

Products related to Dystroglycan Gene:

82 results

OriGene rc201121l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_004393,NP_004384
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5398600
$1,107.81
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene sr301132 RNAi DAG1 Species: Human HPLC purified
Application:
RNA Interference
Gene:
Dystroglycan 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3340920
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-XL4
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • U6 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to Dystroglycan

  • DystroGlycaN (dgn-1)
  • dystroglycan 1 L homeolog (dag1.L)
  • DystroGlycaN (dgn-2)
  • DystroGlycaN (dgn-3)
  • dystroglycan 1 (DAG1)
  • dystroglycan 1 S homeolog (dag1.S)
  • dystroglycan 1 (Dag1)
  • dystroglycan 1 (dag1)
  • Dystroglycan (Dg)
  • dystroglycan (LOC408826)
  • clusterin (Clu)
  • lymphocyte antigen 6 complex (Ly6)
  • 156DAG
  • 156dag
  • A3a
  • a3a
  • AGRNR
  • agrnr
  • Ala-1
  • APOJ
  • atu
  • CG18250
  • CLI
  • CT41273
  • D9Wsu13e
  • DAG
  • dag
  • dag1
  • DAG1
  • dg
  • DG
  • dgn
  • DmDG
  • Dmel\\CG18250
  • Dp71
  • Dp427
  • dys
  • GB14967
  • H9/25
  • LOC398500
  • Ly-6
  • Ly-27
  • Ly27
  • MDDGC7
  • MDDGC9
  • MGC53537
  • RAB7
  • RATTRPM2B
  • SGP-2
  • SGP2
  • SP-40
  • SP40
  • TRPM-2
  • Trpm2
  • TRPM2B
  • Trpmb
  • wu:fb83d06
  • wu:fi25f06
  • wu:fi37b08
  • zgc:109786

Gene-IDs for different species

Protein level used designations for Dystroglycan

  • DystroGlycaN family member (dgn-1)
  • dystroglycan
  • DystroGlycaN family member (dgn-2)
  • DystroGlycaN family member (dgn-3)
  • dystrophin-associated glycoprotein 1
  • dystroglycan 1
  • dystroglycan 1 (dystrophin-associated glycoprotein 1)
  • RAB7, member RAS oncogene family
  • glycine cleavage system T-protein
  • alpha-dystroglycan
  • beta-dystroglycan
  • dystrophin associated glycoprotein 1
  • CG18250-PA
  • CG18250-PB
  • CG18250-PC
  • CG18250-PD
  • Dg-PA
  • Dg-PB
  • Dg-PC
  • Dg-PD
  • atsugari
  • dystroglycan-like
  • dimeric acid glycoprotein
  • sulfated glycoprotein 2
  • testosterone repressed prostate message 2
  • testosterone-repressed prostate message
  • testostrone-repressed prostate message 2
  • dystrophin-associated glycoprote
Other products related to Dystroglycan such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here: