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Dystroglycan (Dystroglycan 1, DAG1)

Short Description: Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010].
More information related to gene Dystroglycan.

Products related to Dystroglycan Gene:

82 results :

Human DAG1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4474528
Datasheet
Catalog No. ABIN4474528
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Insert length:
2688 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human DAG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_004393
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5289689
Datasheet
Catalog No. ABIN5289689
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_004393
Species:
Human
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DAG1
Format:
Viral Particles
Storage:
-80 °C
Mouse DAG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_010017
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5289691
Datasheet
Catalog No. ABIN5289691
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_010017
Species:
Mouse
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dag1
Format:
Viral Particles
Storage:
-80 °C
Human DAG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_004393
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5174094
Datasheet
Catalog No. ABIN5174094
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_004393
Species:
Human
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of DAG1
Format:
Viral Particles
Storage:
-80 °C
Mouse DAG1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_010017
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5174096
Datasheet
Catalog No. ABIN5174096
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_010017
Species:
Mouse
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Dag1
Format:
Viral Particles
Storage:
-80 °C
Human DAG1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4760903
Datasheet
Catalog No. ABIN4760903
Type:
cDNA
Application:
Cloning
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Insert length:
2688 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human DAG1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4829898
Datasheet
Catalog No. ABIN4829898
Type:
cDNA
Application:
Cloning
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Insert length:
2688 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human DAG1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4700769
Datasheet
Catalog No. ABIN4700769
Type:
cDNA
Application:
Cloning
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Insert length:
2688 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human DAG1 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4435623
Datasheet
Catalog No. ABIN4435623
Type:
cDNA
Application:
Protein Expression
Gene:
Dystroglycan 1 (DAG1)
Species:
Human
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Insert length:
2688 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human DAG1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_004393
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5289688
Datasheet
Catalog No. ABIN5289688
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Dystroglycan 1 (DAG1)
NCBI Accession:
NM_004393
Species:
Human
Synonyms:
dgn-1, dag1.L, dgn-2, dgn-3, DAG1, dag1.S, Dag1, dag1, Dg, LOC408826, Clu, Ly6
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of DAG1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCas-Guide
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-XL4
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • U6 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to Dystroglycan

  • DystroGlycaN (dgn-1)
  • dystroglycan 1 L homeolog (dag1.L)
  • DystroGlycaN (dgn-2)
  • DystroGlycaN (dgn-3)
  • dystroglycan 1 (DAG1)
  • dystroglycan 1 S homeolog (dag1.S)
  • dystroglycan 1 (Dag1)
  • dystroglycan 1 (dag1)
  • Dystroglycan (Dg)
  • dystroglycan (LOC408826)
  • clusterin (Clu)
  • lymphocyte antigen 6 complex (Ly6)
  • 156DAG
  • 156dag
  • A3a
  • a3a
  • AGRNR
  • agrnr
  • Ala-1
  • APOJ
  • atu
  • CG18250
  • CLI
  • CT41273
  • D9Wsu13e
  • DAG
  • dag
  • dag1
  • DAG1
  • dg
  • DG
  • dgn
  • DmDG
  • Dmel\\CG18250
  • Dp71
  • Dp427
  • dys
  • GB14967
  • H9/25
  • LOC398500
  • Ly-6
  • Ly-27
  • Ly27
  • MDDGC7
  • MDDGC9
  • MGC53537
  • RAB7
  • RATTRPM2B
  • SGP-2
  • SGP2
  • SP-40
  • SP40
  • TRPM-2
  • Trpm2
  • TRPM2B
  • Trpmb
  • wu:fb83d06
  • wu:fi25f06
  • wu:fi37b08
  • zgc:109786

Gene-IDs for different species

Protein level used designations for Dystroglycan

  • DystroGlycaN family member (dgn-1)
  • dystroglycan
  • DystroGlycaN family member (dgn-2)
  • DystroGlycaN family member (dgn-3)
  • dystrophin-associated glycoprotein 1
  • dystroglycan 1
  • dystroglycan 1 (dystrophin-associated glycoprotein 1)
  • RAB7, member RAS oncogene family
  • glycine cleavage system T-protein
  • alpha-dystroglycan
  • beta-dystroglycan
  • dystrophin associated glycoprotein 1
  • CG18250-PA
  • CG18250-PB
  • CG18250-PC
  • CG18250-PD
  • Dg-PA
  • Dg-PB
  • Dg-PC
  • Dg-PD
  • atsugari
  • dystroglycan-like
  • dimeric acid glycoprotein
  • sulfated glycoprotein 2
  • testosterone repressed prostate message 2
  • testosterone-repressed prostate message
  • testostrone-repressed prostate message 2
  • dystrophin-associated glycoprote
Other products related to Dystroglycan such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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