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FAS (TNF Receptor Superfamily, Member 6, FAS)

Short Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011].
More information related to gene FAS.

Products related to FAS Gene:

74 results

gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_139194
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118975
$1,450.62
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_139194
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118976
$666.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740600
$174.10
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_007987
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740601
$174.10
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_001146708
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740602
$781.20
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_139194
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740603
$781.20
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
TNF Receptor Superfamily, Member 6 (FAS)
Gene ID:
355 (Human, FAS)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5314445
$215.19
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 19 Business Days
OriGene mc208465 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NP_032013
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3292749
$445.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sr410920 RNAi FAS Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
TNF Receptor Superfamily, Member 6
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3267019
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene mc208466 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Fas (TNF Receptor Superfamily, Member 6) (FAS)
NCBI Accession:
NM_001146708,NP_001140180
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3292750
$163.35
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Images available
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to FAS

  • Fas ligand (FASLG)
  • Fas cell surface death receptor (FAS)
  • Fas (TNF receptor superfamily member 6) (Fas)
  • Fas cell surface death receptor (Fas)
  • Fas cell surface death receptor (fas)
  • AI196731
  • ALPS1A
  • ALPS1B
  • APO-1
  • APO1
  • APT1
  • APT1LG1
  • APTL
  • CD95
  • CD95-L
  • CD95L
  • CD178
  • FAS1
  • FASL
  • FASTM
  • lpr
  • TNFR6
  • TNFRSF6
  • Tnfrsf6
  • TNFSF6

Gene-IDs for different species

Protein level used designations for FAS

  • CD95 ligand
  • apoptosis (APO-1) antigen ligand 1
  • apoptosis antigen ligand
  • fas antigen ligand
  • tumor necrosis factor (ligand) superfamily, member 6
  • tumor necrosis factor ligand superfamily member 6
  • APO-1 cell surface antigen
  • CD95 antigen
  • Delta Fas/APO-1/CD95
  • FAS 827dupA
  • FASLG receptor
  • Fas (TNF receptor superfamily, member 6)
  • Fas AMA
  • TNF receptor superfamily member 6
  • apoptosis antigen 1
  • apoptosis-mediating surface antigen FAS
  • tumor necrosis factor receptor superfamily member 6
  • tumor necrosis factor receptor superfamily, member 6
  • Fas antigen
  • Fas (TNF receptor superfamily member)
  • apo-1 antigen
  • lymphoproliferation
  • Fas antigen (ATP1)
  • Fas receptor
  • Tumor necrosis factor receptor superfamily, member 6
  • apoptosis (APO-1) antigen 1 ( FAS ), member 6
  • Fas receptor CD95
Other products related to FAS such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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