FEN1 (Flap Structure-Specific Endonuclease 1, FEN1)
Short Description: The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008].
More information related to gene FEN1.
More information related to gene FEN1.
Products related to FEN1 Gene:
Recommended next Filters:
64 results
OriGene rc201785l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Flap Structure-Specific Endonuclease 1 (FEN1)
- NCBI Accession:
- NM_004111,NP_004102
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5401790
$976.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc201785
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Flap Structure-Specific Endonuclease 1 (FEN1)
- NCBI Accession:
- NM_004111,NP_004102
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5401786
$679.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc201785l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Flap Structure-Specific Endonuclease 1 (FEN1)
- NCBI Accession:
- NM_004111,NP_004102
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5401788
$976.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr301562
RNAi
FEN1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Flap Structure-Specific Endonuclease 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3341349
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to FEN1
- flap structure-specific endonuclease 1 (FEN1)
- flap endonuclease 1-like (LOC100808044)
- Flap endonuclease-1 (Bm1_49605)
- 5'-3' exonuclease family protein (AT5G26680)
- flap structure specific endonuclease 1 (Fen1)
- flap structure-specific endonuclease 1 (fen1)
- flap structure-specific endonuclease 1 L homeolog (fen1.L)
- flap structure-specific endonuclease 1 (Fen1)
- nuclease, Rad2 family (FEN1)
- AW538437
- cb879
- FEN-1
- fen-1
- FEN1
- fen1
- MF1
- mf1
- RAD2
- rad2
- xFEN1a
Gene-IDs for different species
Protein level used designations for FEN1
- flap endonuclease 1
- Flap structure-specific endonuclease 1
- flap structure-specific endonuclease 1
- DNase IV
- maturation factor 1
- maturation factor-1
- 5' nuclease xFEN1a
- FEN-1-A
- flap endonuclease 1-A
- flap structure-specific endonuclease 1-A
- xFEN-1a
- FEN-1
Proteomics products related to FEN1 Gene
Other products related to FEN1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:
