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FEN1 (Flap Structure-Specific Endonuclease 1, FEN1)

Short Description: The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008].
More information related to gene FEN1.

Products related to FEN1 Gene:

64 results :

Human FEN1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5740614
Datasheet
Catalog No. ABIN5740614
Type:
ORF
Application:
Cloning
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
Species:
Human
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Insert length:
1143 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human FEN1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4475630
Datasheet
Catalog No. ABIN4475630
Type:
cDNA
Application:
Protein Expression
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
Species:
Human
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Insert length:
1143 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat FEN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_053430
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234360
Datasheet
Catalog No. ABIN5234360
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_053430
Species:
Rat
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fen1
Format:
Viral Particles
Storage:
-80 °C
Mouse FEN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_007999
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234358
Datasheet
Catalog No. ABIN5234358
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_007999
Species:
Mouse
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fen1
Format:
Viral Particles
Storage:
-80 °C
Human FEN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_004111
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234356
Datasheet
Catalog No. ABIN5234356
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_004111
Species:
Human
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FEN1
Format:
Viral Particles
Storage:
-80 °C
Human FEN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_004111
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234355
Datasheet
Catalog No. ABIN5234355
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_004111
Species:
Human
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FEN1
Format:
Viral Particles
Storage:
-80 °C
Human FEN1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_004111
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5234354
Datasheet
Catalog No. ABIN5234354
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_004111
Species:
Human
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FEN1
Format:
Viral Particles
Storage:
-80 °C
Mouse FEN1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_007999
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119000
Datasheet
Catalog No. ABIN5119000
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_007999
Species:
Mouse
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fen1
Format:
Viral Particles
Storage:
-80 °C
Rat FEN1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_053430
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5119002
Datasheet
Catalog No. ABIN5119002
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_053430
Species:
Rat
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Fen1
Format:
Viral Particles
Storage:
-80 °C
Human FEN1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_004111
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5118997
Datasheet
Catalog No. ABIN5118997
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Flap Structure-Specific Endonuclease 1 (FEN1)
NCBI Accession:
NM_004111
Species:
Human
Synonyms:
FEN1, LOC100808044, Bm1_49605, AT5G26680, Fen1, fen1, fen1.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of FEN1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to FEN1

  • flap structure-specific endonuclease 1 (FEN1)
  • flap endonuclease 1-like (LOC100808044)
  • Flap endonuclease-1 (Bm1_49605)
  • 5'-3' exonuclease family protein (AT5G26680)
  • flap structure specific endonuclease 1 (Fen1)
  • flap structure-specific endonuclease 1 (fen1)
  • flap structure-specific endonuclease 1 L homeolog (fen1.L)
  • flap structure-specific endonuclease 1 (Fen1)
  • nuclease, Rad2 family (FEN1)
  • AW538437
  • cb879
  • FEN-1
  • fen-1
  • FEN1
  • fen1
  • MF1
  • mf1
  • RAD2
  • rad2
  • xFEN1a

Gene-IDs for different species

Protein level used designations for FEN1

  • flap endonuclease 1
  • Flap structure-specific endonuclease 1
  • flap structure-specific endonuclease 1
  • DNase IV
  • maturation factor 1
  • maturation factor-1
  • 5' nuclease xFEN1a
  • FEN-1-A
  • flap endonuclease 1-A
  • flap structure-specific endonuclease 1-A
  • xFEN-1a
  • FEN-1
Other products related to FEN1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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