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GAD65 (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa), GAD2)

Short Description: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008].
More information related to gene GAD65.

Products related to GAD65 Gene:

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63 results

Human GAD2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5750458
Catalog No. ABIN5750458
Type:
ORF
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Insert length:
1758 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human GAD2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4484695
Catalog No. ABIN4484695
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Insert length:
1758 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat GAD2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
NCBI Accession:
NM_012563
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5137870
Catalog No. ABIN5137870
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
NCBI Accession:
NM_012563
Species:
Rat
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gad2
Format:
Viral Particles
Storage:
-80 °C
Mouse GAD2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
NCBI Accession:
NM_008078
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5137868
Catalog No. ABIN5137868
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
NCBI Accession:
NM_008078
Species:
Mouse
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Gad2
Format:
Viral Particles
Storage:
-80 °C
Human GAD2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
NCBI Accession:
NM_000818
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5137866
Catalog No. ABIN5137866
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
NCBI Accession:
NM_000818
Species:
Human
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of GAD2
Format:
Viral Particles
Storage:
-80 °C
Human GAD2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4831898
Catalog No. ABIN4831898
Type:
cDNA
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Insert length:
1758 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human GAD2 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4702768
Catalog No. ABIN4702768
Type:
cDNA
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Insert length:
1758 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human GAD2 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4419609
Catalog No. ABIN4419609
Type:
cDNA
Application:
Protein Expression
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Insert length:
1758 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human GAD2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4628166
Catalog No. ABIN4628166
Type:
cDNA
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
Species:
Human
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Insert length:
1758 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat GAD2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
NCBI Accession:
NM_012563
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5750460
Catalog No. ABIN5750460
Type:
ORF
Application:
Cloning
Gene:
Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2)
NCBI Accession:
NM_012563
Species:
Rat
Synonyms:
GAD2, PTRG_06148, LOC9324534, Gad2, GAD1, gad2
Insert length:
1758 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to GAD65

  • glutamate decarboxylase 2 (GAD2)
  • glutamate decarboxylase 2 (PTRG_06148)
  • glutamate decarboxylase 2 (LOC9324534)
  • glutamate decarboxylase 2 (Gad2)
  • glutamate decarboxylase 1 (GAD1)
  • glutamate decarboxylase 2 (gad2)
  • glutamic acid decarboxylase 2 (Gad2)
  • 6330404F12Rik
  • F12P19.12
  • F12P19_12
  • GAD(65)
  • Gad-2
  • GAD65
  • gad65
  • GLUTAMATE DECARBOXYLASE 2
  • glutamate decarboxylase 2
  • zgc:112198

Gene-IDs for different species

Protein level used designations for GAD65

  • glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • glutamate decarboxylase 2
  • glutamic acid decarboxylase
  • 65 kDa glutamic acid decarboxylase
  • GAD-65
  • Glutamate decarboxylase 2 (islet)
  • glutamate decarboxylase 65 kDa isoform
  • glutamic acid decarboxylase 2
  • glutamic acid decarboxylase 65
  • Glutamate decarboxylase-2 (pancreas)
Other products related to GAD65 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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