Haptoglobin (Haptoglobin, HP)
Short Description: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene Haptoglobin.
More information related to gene Haptoglobin.
Products related to Haptoglobin Gene:
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ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5325331
$215.19
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2 μg
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Synonyms and alternative names related to Haptoglobin
- haptoglobin (HP)
- haptoglobin (hp)
- haptoglobin (Hp)
- haptoglobin-like (LOC479668)
- haptoglobin (LOC101102413)
- BP
- HP
- HP-1
- HP2ALPHA2
- HPA1S
- HPR
- wu:fb64e01
- Zonulin
Gene-IDs for different species
Protein level used designations for Haptoglobin
- haptoglobin
- HpL
- binding peptide
- haptoglobin alpha(1S)-beta
- haptoglobin alpha(2FS)-beta
- haptoglobin, alpha polypeptide
- haptoglobin, beta polypeptide
- zonulin
- liver regeneration-related protein LRRG173
- haptoglobin-related protein
- haptoglobin alpha 1S
Proteomics products related to Haptoglobin Gene
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