HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ beta 1, HLA-DQB1)
Short Description: HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011].
More information related to gene HLA-DQB1.
More information related to gene HLA-DQB1.
Products related to HLA-DQB1 Gene:
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28 results
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
Catalog No. ABIN4437666
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 31 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4703830
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 31 Business Days
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Catalog No. ABIN4703829
$805.29
Plus shipping costs $50.00
500 ng
Shipping to:
United States
Delivery in 21 to 31 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- NCBI Accession:
- XM_001722253
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5205372
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- NCBI Accession:
- XM_001722253
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5090203
$1,511.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- NCBI Accession:
- XM_001722253
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Catalog No. ABIN5205371
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to:
United States
Delivery in 31 to 41 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- NCBI Accession:
- NM_002123
- Gene ID:
- 3119 (Human, HLA-DQB1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4928781
ORF
Clon
Gateway Cloning Vector
pDONR223
Spectinomycin
unconjugated
Catalog No. ABIN5313344
$212.22
Plus shipping costs $50.00
2 μg
Shipping to:
United States
Delivery in 15 to 17 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- NCBI Accession:
- NM_001243961
- Gene ID:
- 3119 (Human, HLA-DQB1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4928780
$199.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 8 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- NCBI Accession:
- NM_001243962
- Gene ID:
- 3119 (Human, HLA-DQB1)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4938771
$199.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 6 Business Days
Synonyms and alternative names related to HLA-DQB1
- major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1)
- major histocompatibility complex, class II, DQ beta 1 (PATR-DQB1)
- major histocompatibility complex, class II, DQ beta 1 (DLA-DQB1)
- major histocompatibility complex, class II, DQ beta 1 (MAMU-DQB1)
- major histocompatibility complex, class II, DQ beta 1 (LOC100172120)
- CELIAC1
- DKFZp469C0237
- DLA-DQB
- HLA-DQB
- IDDM1
- LOC100172120
- MAMU-DQB1
- mhc-DRB
Gene-IDs for different species
Protein level used designations for HLA-DQB1
- HLA class II histocompatibility antigen, DQ beta 1 chain
- MHC DQ beta
- MHC class II DQ beta chain
- MHC class II HLA-DQ beta glycoprotein
- MHC class II antigen DQB1
- MHC class II antigen HLA-DQ-beta-1
- MHC class2 antigen
- lymphocyte antigen
- MHC class II DRB antigen
- MHC class II DLA DQ beta chain
- major histocompatibility complex, class II, DQ beta 1
Proteomics products related to HLA-DQB1 Gene
Other products related to HLA-DQB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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