HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ beta 1, HLA-DQB1)
Short Description: HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011].
More information related to gene HLA-DQB1.
More information related to gene HLA-DQB1.
Products related to HLA-DQB1 Gene:
Recommended next Filters:
28 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- NCBI Accession:
- XM_001722253
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Major Histocompatibility Complex, Class II, DQ beta 1 (HLA-DQB1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Synonyms and alternative names related to HLA-DQB1
- major histocompatibility complex, class II, DQ beta 1 (HLA-DQB1)
- major histocompatibility complex, class II, DQ beta 1 (PATR-DQB1)
- major histocompatibility complex, class II, DQ beta 1 (DLA-DQB1)
- major histocompatibility complex, class II, DQ beta 1 (MAMU-DQB1)
- major histocompatibility complex, class II, DQ beta 1 (LOC100172120)
- CELIAC1
- DKFZp469C0237
- DLA-DQB
- HLA-DQB
- IDDM1
- LOC100172120
- MAMU-DQB1
- mhc-DRB
Gene-IDs for different species
Protein level used designations for HLA-DQB1
- HLA class II histocompatibility antigen, DQ beta 1 chain
- MHC DQ beta
- MHC class II DQ beta chain
- MHC class II HLA-DQ beta glycoprotein
- MHC class II antigen DQB1
- MHC class II antigen HLA-DQ-beta-1
- MHC class2 antigen
- lymphocyte antigen
- MHC class II DRB antigen
- MHC class II DLA DQ beta chain
- major histocompatibility complex, class II, DQ beta 1
Proteomics products related to HLA-DQB1 Gene
Other products related to HLA-DQB1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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