IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1, IMPA1)
Short Description: This gene encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Nov 2009].
More information related to gene IMPA1.
More information related to gene IMPA1.
Products related to IMPA1 Gene:
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66 results
OriGene rc202784
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
- NCBI Accession:
- NM_005536,NP_005527
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5416535
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc227545
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
- NCBI Accession:
- NM_001144878,NP_001138350
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5416536
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc227552
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
- NCBI Accession:
- NM_001144879,NP_001138351
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5416537
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rr208568
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
- NCBI Accession:
- NM_032057,NP_114446
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5416538
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg202784
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5416532
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr302411
RNAi
IMPA1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Inositol(myo)-1(or 4)-Monophosphatase 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342193
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to IMPA1
- inositol monophosphatase 1 (impa1)
- inositol(myo)-1(or 4)-monophosphatase 1 (impa1)
- inositol (myo)-1(or 4)-monophosphatase 1 (Impa1)
- inositol monophosphatase 1 (Impa1)
- inositol monophosphatase (impa1)
- inositol monophosphatase 1 (IMPA1)
- inositol(myo)-1(or 4)-monophosphatase 1 S homeolog (impa1.S)
- inositol(myo)-1(or 4)-monophosphatase 1 (IMPA1)
- 2610002K09Rik
- 2900059K10Rik
- AI325909
- IMP
- IMPA
- impa
- zgc:100926
Gene-IDs for different species
Protein level used designations for IMPA1
- inositol monophosphatase 1
- Inositol monophosphatase
- IMP 1
- IMPase 1
- inositol-1(or 4)-monophosphatase 1
- lithium-sensitive myo-inositol monophosphatase A1
- myo-inositol monophosphatase
Proteomics products related to IMPA1 Gene
Other products related to IMPA1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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